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ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025

A Case of Saddle Nose Deformity Secondary to Lepromatous Leprosy.

Uma Pokala, Ashesh Reddy Poondru, Saisantoshi Laxmi Santhi Swetha M, Vallabhaneni Kavya, Sravani Chukkapally, Naveen Pokala

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Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Uma PokalaDepartment of ENT, Mamata Academy of Medical Sciences, Hyderabad Telangana, 500090 Telangana India.ORCID 0000-0001-6112-0987
Ashesh Reddy PoondruDepartment of ENT, Mamata Medical College, Khammam, 507002 Telangana India.ORCID 0009-0000-3902-2117
Saisantoshi Laxmi Santhi Swetha MDepartment of ENT, Mamata Medical College, Khammam, 507002 Telangana India.ORCID 0009-0006-6889-1892
Vallabhaneni KavyaDepartment of ENT, Mamata Medical College, Khammam, 507002 Telangana India.ORCID 0009-0007-2283-171X
Sravani ChukkapallyDepartment of ENT, Mamata Medical College, Khammam, 507002 Telangana India.ORCID 0009-0003-8950-938X
Naveen PokalaDepartment of Pharmacology, Mamata Academy of Medical Sciences, Hyderabad, 500090 Telangana India.ORCID 0000-0001-7748-5892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeprosy is a chronic infectious disease caused by the Mycobacterium leprae affecting most commonly skin and peripheral nerves. Patients with Lepromatous Leprosy remain asymptomatic for years, and harbor bacteria in the nasal cavity, and these patients are responsible for the transmission of the disease in the community. In the advanced stage (stages 4 and 5) the involvement of nasal septum results in saddle nose deformity in most patients.

methodsIn this post-leprosy elimination era, this is a rare presentation with saddle nose deformity mimicking atrophic rhinitis. It was diagnosed based on the microbiological examination (AFB staining) of the nasal discharge.

resultsZN Stain shows acid-fast bacilli in globi suggestive of Mycobacterium Leprae. On slit examination of the skin smear of the Right ear lobule also showed positive for acid-fast bacilli with bacteriological index 6+.

conclusionIn this post-elimination era, leprosy should also be considered a differential diagnosis for atrophic rhinitis that is not responding to routine treatment. With early diagnosis and timely initiation of appropriate treatment, such damage can be minimized.

Indexed as

AnosmiaAtrophic RhinitisLepromatous LeprosySaddle nose

Identifiers

PMID40065940
PMCPMC11890379

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