ArticleCureus2025
Primary Leptomeningeal Lymphoma Presenting As Rapidly Progressive Hydrocephalus: Diagnosis and Symptom Relief Through Endoscopic Ependymal Biopsy and Third Ventriculostomy.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Primary leptomeningeal lymphoma (PLML) is a rare variant of primary central nervous system lymphoma, distinguished by the absence of parenchymal lesions. We describe an exceptionally rare case of PLML in an 86-year-old woman presenting with hydrocephalus. Magnetic resonance imaging showed ventricular enlargement over a two-week period, accompanied by faint periventricular contrast enhancement. To diagnose and treat her symptoms, an endoscopic ependymal biopsy and third ventriculostomy were performed concurrently, resulting in a pathological diagnosis of diffuse large B-cell lymphoma, specifically PLML, and symptom alleviation. The endoscopic approach proved effective and reasonable for the diagnosis and resolution of this atypical hydrocephalus.
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