Evidence map›Paper›PMID 40065892›Full record

ArticleCureus2025

Optimizing Recovery: Heliox Therapy for Post-extubation Stridor Management.

Nishant Allena, Shalini Penikilapate, Sai Allu, Trupti Vakde

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nishant AllenaPulmonary Medicine, BronxCare Health System, Bronx, USA.
Shalini PenikilapateInternal Medicine, BronxCare Health System, Bronx, USA.
Sai AlluMedicine, BronxCare Health System, Bronx, USA.
Trupti VakdePulmonary and Critical Care, BronxCare Health System, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-extubation stridor poses a significant challenge in critical care settings, often necessitating prompt intervention to prevent respiratory compromise and potential reintubation. This case report details the successful management of post-extubation stridor in a 55-year-old female patient with a complex medical history, using heliox therapy. Heliox, a gas mixture of helium and oxygen, has emerged as a novel therapeutic option in such scenarios, owing to its ability to reduce airway resistance and improve gas flow dynamics. Following the patient's elective intubation for MRI imaging, she developed hoarseness, loud breathing, and stridor upon extubation, indicative of subglottic edema and bilateral vocal cord paralysis. Despite initial treatment with conventional modalities yielding minimal improvement, heliox therapy (70%/30%) with supplemental oxygen was initiated, resulting in significant alleviation of symptoms. Subsequent maintenance therapy with corticosteroids and bronchodilators further facilitated the resolution of respiratory distress. This case underscores the pivotal role of heliox therapy as an effective adjunct in managing post-extubation stridor, offering rapid relief and potentially obviating the need for reintubation. Moreover, it highlights the importance of innovative therapeutic approaches in optimizing outcomes for patients with respiratory distress in critical care settings. However, further research is warranted to elucidate the optimal utilization criteria and long-term efficacy of heliox therapy in this context.

Indexed as

extubation failurehelioxpost-extubation stridortraumatic intubationvocal cord paralysis

Identifiers

PMID40065892
PMCPMC11893200

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.