Evidence map›Paper›PMID 40065861›Full record

ArticleCureus2025

Association Between the Bone Density of Alveolar and General Skeletal Bones in the Young.

Noriyuki Sugino, Hiroko Kuroiwa, Hizuru Osanai, Shinichiro Yamada, Nanae Dewake, Souhei Suzuki, Yoshimi Kawahara, Nobuo Yoshinari, Nobuyuki Udagawa, Akira Taguchi

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Noriyuki SuginoDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Hiroko KuroiwaDepartment of Pediatric Dentistry, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Hizuru OsanaiDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Shinichiro YamadaDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Nanae DewakeDepartment of Operative Dentistry, Endodontology and Periodontology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Souhei SuzukiDepartment of Hard Tissue Research, Graduate School of Oral Medicine, Matsumoto Dental University, Shiojiri, JPN.
Yoshimi KawaharaDepartment of Orthodontics, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Nobuo YoshinariDepartment of Operative Dentistry, Endodontology and Periodontology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Nobuyuki UdagawaDepartment of Biochemistry, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.
Akira TaguchiDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Shiojiri, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Osteoporosis-related fractures are a significant health issue in aging societies, necessitating effective screening and prevention strategies. While panoramic radiographs are widely used for osteoporosis screening via mandibular cortical bone morphology, there is insufficient consensus on the quantitative analysis of alveolar bone mineral density (al-BMD) using intraoral radiographs. This study aimed to measure al-BMD in young adults and investigate its relationship with general skeletal bone mineral density (gs-BMD) at the lumbar spine (LSBMD) and femoral neck (FNBMD). Additionally, the influence of biological factors, such as body weight and height, on BMD was assessed. Methodology A total of 53 young adults (34 males, 19 females, mean age: 26.0 years) participated in this study. Intraoral radiographs with calcium carbonate reference standards quantified al-BMD at three mandibular premolar regions. gs-BMD was measured using dual-energy X-ray absorptiometry (DXA). Correlations among al-BMD, gs-BMD, and biological factors were analyzed. Results Results showed no significant differences between age, sex, body height, body weight, al-BMD, and gs-BMD. Age was correlated with FNBMD but not al-BMD as well as LSBMD. Body weight positively correlated with LSBMD (r = 0.437, P = 0.001) but negatively with FNBMD (r = -0.412, P = 0.002). No significant correlations were observed between al-BMD and gs-BMD or biological factors. Conclusion These findings suggest that al-BMD may not necessarily reflect gs-BMD changes and is strongly influenced by local factors in the oral cavity. This highlights the importance of evaluating al-BMD independently of gs-BMD. Future studies with larger sample sizes and additional factors influencing al-BMD are needed to validate these results.

Indexed as

alveolar bone mineral densitybone mineral density (bmd)general skeletal bone mineral densityintraoral radiographsosteoporosis screening

Identifiers

PMID40065861
PMCPMC11891509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.