ArticleCureus2025
Acute Ethanol-Disulfiram Reaction Presenting With Hemodynamic Instability: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Ethanol as a Modifier of Drug Toxicity in Humans: Pathways of Toxicity and Organ-Level Consequences.International journal of molecular sciences · 2026Review
- Article
- Fatal Disulfiram-Ethanol Reaction in a Patient With Preexisting Cardiac Comorbidities: A Case Report.Cureus · 2025Article
- Disulfiram-like reaction with ornidazole: A case report of a rare interaction.Turkish journal of emergency medicineArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol-disulfiram reaction (EDR) is a rare but potentially life-threatening condition characterized by a constellation of symptoms, including flushing, hypotension, tachycardia, nausea, and vomiting. We report the case of a 52-year-old male patient who presented with acute hemodynamic instability after inadvertent alcohol consumption while on disulfiram therapy for alcohol dependence. The patient exhibited signs of shock, including hypotension and hyperlactatemia, but responded promptly to fluid resuscitation and transient vasopressor support. A detailed history confirmed the diagnosis of EDR. This case highlights the importance of recognizing EDR as a differential diagnosis in patients with acute hemodynamic instability and a relevant clinical history. Early identification and supportive management are crucial for favorable outcomes.
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Registered trials
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