Evidence map›Paper›PMID 40065847›Full record

ArticleClinical kidney journal2025

Digital physical activity intervention via the Kidney BEAM platform in patients with polycystic kidney disease: a randomized controlled trial.

Juliet Briggs, Elizabeth Ralston, Thomas J Wilkinson, Christy Walklin, Emmanuel Mangahis, Hannah M L Young, Ellen M Castle, Roseanne E Billany, Elham Asgari, Sunil Bhandari and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mental health and kidney disease.Nature reviews. Nephrology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Juliet BriggsRenal Therapies Department, King's College Hospital, London, UK.
Elizabeth RalstonDepartment of Women's and Children's Health, Faculty of Life Sciences, King's College London, London, UK.
Thomas J WilkinsonNational Institute of Health Research Leicester Biomedical Research Centre, Leicester, UK.
Christy WalklinRenal Therapies Department, King's College Hospital, London, UK.
Emmanuel MangahisRenal Therapies Department, King's College Hospital, London, UK.
Hannah M L YoungLeicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, UK.
Ellen M CastleCurtin School of Allied Health, Faculty of Health Sciences, Curtin University, Western Australia, Australia.
Roseanne E BillanyDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.ORCID https://orcid.org/0000-0001-9610-4717
Elham AsgariDepartment of Nephrology, Guys and St Thomas's Hospital, London, UK.
Sunil BhandariDepartment of Nephrology, Hull University Teaching Hospitals NHS Trust, Hull, UK.ORCID https://orcid.org/0000-0002-0996-9622
Kate BramhamCentre for Nephrology, Urology and Transplantation, Faculty of Life Sciences, King's College London, London, UK.
James O BurtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Jackie CampbellFaculty of Health, Education and Society, University of Northampton, Northampton, UK.
Joseph ChilcotDepartment of Psychology, Psychology & Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0001-6427-4690
Vashist DeelchandDepartment of Nephrology Royal Free Hospital, London, UK.
Alexander HamiltonDepartment of Nephrology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.ORCID https://orcid.org/0000-0002-0730-4897
Mark JeskyDepartment of Nephrology, Nottingham NHS Trust, Nottingham, UK.
Philip A KalraDepartment of Nephrology Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
Kieran McCaffertyDepartment of Nephrology, Barts Health NHS Trust, London, UK.
Andrew C NixonDepartment of Renal Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.ORCID https://orcid.org/0000-0002-4093-6204
Zoe L SaynorSchool of Health Sciences, University of Southampton, Southampton, UK.
Maarten W TaalCentre for Kidney Research and Innovation, School of Medicine, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0002-9065-212X
James TollittDepartment of Nephrology Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK.
David C WheelerDepartment of Renal Medicine, University College London, London, UK.
Jamie MacdonaldInstitute for Applied Human Physiology, Bangor University, Bangor, UK.
Sharlene A GreenwoodRenal Therapies Department, King's College Hospital, London, UK.ORCID https://orcid.org/0000-0001-9485-4645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In people living with polycystic kidney disease (PKD), physical inactivity may contribute to poor health-related quality of life (HRQoL). To date, no research has elucidated the impact of a PKD-specific physical activity programme on HRQoL and physical health. This substudy of the Kidney BEAM Trial evaluated the impact of a PKD-specific 12-week educational and physical activity digital health intervention for people living with PKD. Methods: This study was a mixed-methods, single-blind, randomized waitlist-controlled trial. Sixty adults with a diagnosis of PKD were randomized 1:1 to the intervention or a waitlist control group. Primary outcome was difference in the Kidney Disease QoL Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between baseline and 12 weeks. Six participants completed individualized semi-structured interviews. Results: All 60 individuals (mean 53 years, 37% male) were included in the intention-to-treat analysis. At 12 weeks, there was a significant difference in mean adjusted change in KDQoL MCS score between the intervention group and waitlist control [4.2 (95% confidence interval 1.0-7.4) arbitrary units, Conclusion: A PKD-specific digital health educational and physical activity intervention is acceptable and has the potential to improve HRQoL. Further research is needed to better understand how specific education and lifestyle management may help to support self-management behaviour.

Indexed as

digital health interventionexercisephysical activitypolycystic kidney diseasequality of life

Identifiers

PMID40065847
PMCPMC11892433

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.