Evidence map›Paper›PMID 40065835›Full record

ArticleContemporary clinical trials communications2025

Bridging the gap: Understanding Latino willingness to participate in public health and clinical trials research across diverse subgroups.

Mary A Garza, Yan Li, Craig S Fryer, Luciana C Assini-Meytin, Segen Ghebrendrias, Christina Celis Puga, James Butler Lll, Sandra C Quinn, Stephen B Thomas

Abstract read
In one paragraph

Article in Contemporary clinical trials communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Population Admixture andJournal of cardiovascular development and disease · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mary A GarzaDepartment of Public Health, College of Health and Human Services, California State University, Fresno, United States.
Yan LiJoint Program in Survey Methodology & Department of Epidemiology and Biostatistics, University of Maryland, College Park, United States.
Craig S FryerDepartment of Behavioral and Community Health, School of Public Health, University of Maryland College Park, United States.
Luciana C Assini-MeytinDepartment of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, United States.
Segen GhebrendriasDepartment of Public Health, College of Health and Human Services, California State University, Fresno, United States.
Christina Celis PugaDepartment of Public Health, College of Health and Human Services, California State University, Fresno, United States.
James Butler LllDepartment of Behavioral and Community Health, School of Public Health, University of Maryland College Park, United States.
Sandra C QuinnMaryland Center for Health Equity, School of Public Health, University of Maryland College Park, United States.
Stephen B ThomasMaryland Center for Health Equity, School of Public Health, University of Maryland College Park, United States.

Funding

Uncovering and Addressing Cultural Beliefs Behind Vaccine Racial Disparities P20MD006737 · NIMHD · UNIV OF MARYLAND, COLLEGE PARK · PI QUINN, SANDRA CROUSE, THOMAS, STEPHEN B. · 2012 to 2016
$5.9M
Building Trust Between Minorities and ResearchersRC2MD004766 · NIMHD · UNIV OF MARYLAND, COLLEGE PARK · PI QUINN, SANDRA CROUSE, THOMAS, STEPHEN B. · 2009 to 2010
$4.0M
Sci-Tech Core-Maryland Population Research CenterP2CHD041041 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI MICHAEL S. RENDALL · 2018 to 2026
$3.9M
Smoking Cessation among Residents of Public HousingK01CA134939 · NCI · UNIV OF MARYLAND, COLLEGE PARK · PI BUTLER III, JAMES · 2009 to 2013
$652k
Correlates of Nicotine Dependence among Urban African American YouthK01CA148789 · NCI · UNIV OF MARYLAND, COLLEGE PARK · PI FRYER, CRAIG S. · 2010 to 2014
$633k
African Americans and Colorectal Cancer: A Multilevel Model to Assess Factors forK01CA140358 · NCI · UNIV OF MARYLAND, COLLEGE PARK · PI GARZA, MARY A · 2010 to 2012
$392k
NCI NIH HHS K01 CA134939NCI NIH HHS K01 CA140358NCI NIH HHS K01 CA148789NICHD NIH HHS P2C HD041041NIMHD NIH HHS P20 MD006737NIMHD NIH HHS RC2 MD004766
6 · The paper itself

Abstract

Background: The underrepresentation of racial and ethnic minoritized populations in public health and clinical trials research remains a persistent issue. Yet, despite the growing body of literature investigating Latino participation in research, studies examining differences Methods: We conducted a population-based household telephone survey with Latino adults (N = 1264), with 68 % Mexican/Mexican American, 11 % Central/South American, 8 % Puerto Rican and the remaining 13 % self-identified as "Other". The "Building Trust Survey," included valid standardized instruments designed to assess knowledge of research, human subjects' protections, previous participation in research, immigrant status (nativity), length of time in the US, and country of origin. Results: The study found that Latinos who immigrated to the US as teens or young adults were more willing to participate in medical research than those born in the US. Willingness to "take" something in a study varied by Latino subgroup, immigration age, gender, and age. Analysis highlighted that Mexican/Mexican Americans (76 %) and Central/South Americans (74 %) indicated a willingness to participate in research but also were less likely to have been "Asked" to participate in research (9 % and 6 % respectively) compared to the other subgroups (p < .05). Conclusions: Insights from this study will inform the development of culturally tailored interventions aimed at successfully recruiting and retaining Latino populations in public health and clinical trials research, thereby contributing to more equitable and representative health outcomes.

Indexed as

Clinical trial researchHealth disparitiesLatino populationWillingness to participate in research

Identifiers

PMID40065835
PMCPMC11891600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.