ArticlePreventive medicine reports2025
Leveraging spatiotemporal Bayesian analysis to unravel polysubstance use and overdose risk: Opportunities and challenges.
Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Daily polysubstance use associated with HIV, HCV, and non-fatal overdose among people who inject drugs: A latent class analysis using nationwide data.Drug and alcohol dependence · 2026Article
- A population-based study exploring racial and gender inequities in polysubstance-related deaths across the United States from 2004 to 2022.Addiction (Abingdon, England) · 2026Article
- An Epidemic of Complexity: Polysubstance Use Fatal Overdose Typologies Across Cook County, Illinois, Neighborhoods, 2017‒2022.American journal of public health · 2026Article
- Spatiotemporal clustering of state-level opioid, opioid-stimulant, and opioid-benzodiazepine polysubstance deaths across the U.S.: Hierarchical agglomerative clustering analysis.Drug and alcohol dependence · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In the current wave of the opioid epidemic, the prevalence of polysubstance use continues to complicate drug-related deaths. Most studies to date use non-spatial statistical approaches to examine the association between polysubstance use and overdose risk, without considering the spatial distribution of these latent sub-patterns of use. This paper describes the utility and potential impact of using disease mapping and Bayesian spatiotemporal approaches for analyzing and monitoring polysubstance use and overdose risk to better respond to the ongoing opioid epidemic. We discuss the application of Bayesian spatiotemporal approaches in analyzing polysubstance use among people who use drugs. Bayesian spatiotemporal analyses offer a salient approach to detecting localized distributions of overdose events and tailor local interventions to community needs in order to reduce polysubstance use and related adverse health among people who use drugs. This can help improve precision and efficacy response in reducing polysubstance use adverse outcomes and optimize resource allocation.
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Registered trials
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