Evidence map›Paper›PMID 40065720›Full record

ArticleActa biochimica et biophysica Sinica2025

Yuming Jia, Zeng Ye, Xin Wang, Yanli Deng, Chao Wang, Zhilei Zhang, Guixiong Fan, Wuhan Yang, Xiaowu Xu, Yi Qin and 1 more

Abstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuming JiaDepartment of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Zeng YeDepartment of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200031, China.
Xin WangDepartment of Emergency, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Yanli DengDepartment of Clinical Laboratory, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Chao WangDepartment of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Zhilei ZhangDepartment of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Guixiong FanDepartment of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200031, China.
Wuhan YangDepartment of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Xiaowu XuDepartment of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200031, China.
Yi QinDepartment of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai 200031, China.
Li PengDepartment of Hepatobiliary Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a type of programmed death characterized by iron-dependent lipid peroxidation, and targeting ferroptosis has been shown to efficiently kill highly aggressive cancer cells. Previously, we confirmed that nuclear receptors regulate ferroptosis in pancreatic cancer. However, whether nuclear receptor co-activators regulate ferroptosis is unclear. Here, we show that knocking down the nuclear receptor co-activator,

Indexed as

DeoxycytidineDrug Resistance, NeoplasmFerroptosisNuclear Receptor CoactivatorsPancreatic NeoplasmsAntimetabolites, AntineoplasticCarbolinesCell Line, TumorGemcitabineGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansAntimetabolites, AntineoplasticCarbolinesDeoxycytidineGemcitabineNuclear Receptor CoactivatorsRSL3 compoundferroptosisgemcitabineNCOA6pancreatic cancer

Identifiers

PMID40065720
PMCPMC12368539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.