Evidence map›Paper›PMID 40065646›Full record

ArticleMagnetic resonance in medicine2025

Elastographic magnetization prepared imaging with rapid encoding.

Alex M Cerjanic, Alexa M Diano, Curtis L Johnson

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alex M CerjanicDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.
Alexa M DianoDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.
Curtis L JohnsonDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware, USA.ORCID https://orcid.org/0000-0002-7760-131X

Funding

MRI Measurement of the Mechanical Vulnerability of the BrainU01NS112120 · NINDS · WASHINGTON UNIVERSITY · PI BAYLY, PHILIP V · 2019 to 2023
$3.7M
High-Resolution, Anisotropic MR Elastography of the BrainR01EB027577 · NIBIB · UNIVERSITY OF DELAWARE · PI BAYLY, PHILIP V, JOHNSON, CURTIS L · 2019 to 2022
$2.7M
Mechanical integrity of memory systems in mild cognitive impairmentR01AG058853 · NIA · UNIVERSITY OF DELAWARE · PI JOHNSON, CURTIS L · 2018 to 2022
$2.3M
NIA NIH HHS R01 AG058853NIA NIH HHS R01-AG058853NIBIB NIH HHS R01 EB027577NIBIB NIH HHS R01-EB027577NINDS NIH HHS U01 NS112120NINDS NIH HHS U01-NS112120
6 · The paper itself

Abstract

purposeTo introduce a novel sequence for achieving fast, whole-brain MR elastography data through the introduction of a magnetization preparation block for motion encoding along with rapid imaging readouts. THEORY AND

methodsWe implemented MRE motion encoding in a magnetization preparation pulse sequence block, where spins are excited, motion encoded, and then stored longitudinally. This magnetization is accessed through a train of rapid gradient echoes and encoded with a 3D stack-of-spirals trajectory. Spoilers are included to crush unprepared magnetization and avoid image artifacts. We demonstrate the feasibility of the proposed method in capturing MRE displacement data for estimating mechanical properties and accelerating scan times.

resultsWe measured stability of phase across gradient echo readouts in the readout train after magnetization preparation. Additionally, we obtained displacement fields with high OSS-SNR with retrospective sampling and differences in average stiffness properties (NRMSE) of 3.6% (

conclusionMagnetization preparation for MRE is feasible and can accelerate brain MRE scans, producing high-quality mechanical property maps at 2.5 mm isotropic resolution in 1 min 20 s.

Indexed as

BrainElasticity Imaging TechniquesImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsArtifactsHumansImaging, Three-DimensionalMotionPhantoms, ImagingSignal-To-Noise Ratioaccelerationbrainelastographyspiralstiffness

Identifiers

PMID40065646
PMCPMC12532434

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.