ArticleVeterinary medicine and science2025
Effects of Age, Sex, and Exercise on Measurement of Serum CTnI Levels and Some Parameters Related to the Cardiovascular Capacity of Caspian Horses.
Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to their high specificity and exclusive cardiac myocyte sensitivity, cardiac troponins T and I (cTnT, cTnI) are currently regarded as ideal biomarkers to identify cardiomyocyte damage, myocardial injury, myocardial infarction, and chronic heart failure. In fact, cTnI is considered the most reliable biomarker for diagnosing heart-related issues. This study aimed to investigate the effects of age, gender, and exercise training on serum cTnI levels and various parameters related to the cardiovascular capacity of Caspian horses. For this purpose, 50 adult Caspian horses over 3 years old, both male and female, were selected from horse breeding centres and clubs in the provinces of Tehran, Alborz, and Gilan. To account for age-related differences, the horses were divided into three groups: Group A (less than 5 years), Group B (between 5 and 10 years), and Group C (over 10 years). To measure cTnI levels, 10 mL of blood was collected from the jugular vein of each horse using a venoject blood collection tube before exercise and another 10 mL 2 h post-exercise. The samples were refrigerated and centrifuged for 30 min after collection. Two millilitres of serum obtained from each horse at both time points was stored at -20°C for subsequent analysis. Troponin I levels were measured in the laboratory using the electrochemical luminescence (ECL) method. The results of this study reveal for the first time that the normal average of serum cTnI, packed cell volume (PCV), and blood haemoglobin (Hb) levels in Caspian horses is 2.5 ng/L, 35.52%, and 12.1%, respectively. Furthermore, the findings indicate that exercise significantly increases serum levels of cTnI, PCV, and blood haemoglobin; however, age and gender did not appear to affect these measured parameters. Therefore, it can be concluded that exercise stimulates the release of troponin due to myocardial injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.