Evidence map›Paper›PMID 40065453›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2025

Genome-Wide Association Study Identifying a Novel Gene Related to a History of Febrile Convulsions in Patients With Focal Epilepsy.

Joonho Kim, Hye Jeong Lee, Hyung Jun Park, Ji Hyun Lee, Won-Joo Kim

Abstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Journal of clinical medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joonho KimDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9020-8195
Hye Jeong LeeDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5402-9189
Hyung Jun ParkDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4165-8901
Ji Hyun LeeDepartment of Clinical Pharmacology and Therapeutics, Kyung Hee University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3640-2928
Won-Joo KimDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea. kzoo@yuhs.ac.ORCID https://orcid.org/0000-0002-5850-010X

Funding

Korea Health Industry Development InstituteYonsei University College of Medicine 6-2011-0134
6 · The paper itself

Abstract

background and purposeThe risk factors for developing epilepsy following febrile convulsion (FC) have been studied extensively, but the underlying genetic components remain largely unexplored. Our objective here was to identify the risk loci related to FC through a genome-wide association study of Korean epilepsy patients.

methodsWe examined associations between a history of FC and single-nucleotide polymorphisms (SNPs) in data obtained from 125 patients with focal epilepsy: 28 with an FC history and 97 without an FC history.

resultsAmong 288,394 SNPs, 5 candidate SNPs showed

conclusionsThis novel discovery of SNPs upstream of

Indexed as

febrile convulsionfocal epilepsygenome-wide association studypolymorphismprospero-related homeobox 1 proteinsingle nucleotide

Identifiers

PMID40065453
PMCPMC11896740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.