Evidence map›Paper›PMID 40065402›Full record

ArticleJournal of intensive care2025

Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT.

Sireesha Chilakapati, Jyothi Koteswara Rao, Bharat Paliwal

Abstract readLetter
In one paragraph

Article in Journal of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sireesha ChilakapatiDepartment of Anaesthesiology and Critical Care, AIIMS, Phase II, Basani Industrial Area,, Jodhpur, 342005, Rajasthan, India. sirishac3@gmail.com.ORCID http://orcid.org/0000-0003-4806-8322
Jyothi Koteswara RaoDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, India.ORCID http://orcid.org/0000-0002-9284-6761
Bharat PaliwalDepartment of Anaesthesiology and Critical Care, AIIMS, Jodhpur, India.ORCID http://orcid.org/0000-0001-7588-9017

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We commend the authors for their insightful study on inspiratory muscle training (IMT) in mechanically ventilated patients with difficult weaning, highlighting the robust use of maximum inspiratory pressure (MIP) as a key outcome. We suggest that a lower baseline maximum inspiratory pressure cutoff could better target patients with significant inspiratory dysfunction, improving the study's precision. Additionally, alternative imputation techniques, such as multiple imputation, could strengthen the handling of missing data. While the sample size calculation was appropriate, the unbalanced group sizes raise concerns about generalisability. Future research could benefit from subgroup analyses, individual response curves, and further investigation into the unexpected adverse effects observed in the low-intensity group to refine the inspiratory muscle training protocols.

Indexed as

Difficult-to-weanExtubation predictionInspiratory muscle trainingMaximal inspiratory pressureMechanical ventilationRespiratory muscle strength

Identifiers

PMID40065402
PMCPMC11892247

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.