Evidence map›Paper›PMID 40065350›Full record

ArticleRespiratory research2025

Epidemiology of idiopathic pulmonary fibrosis in central and Western Pennsylvania.

Faina Linkov, Yue-Fang Chang, Harshitha Ramanan, Richard S Morgan, Kathleen M McTigue, Anne E F Dimmock, Rebecca Bascom, Daniel J Kass

Abstract read
In one paragraph

Article in Respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Faina Linkov *Department of Health, Exercise & Applied Science, John G. Rangos Sr. School of Health Sciences, Duquesne University, Pittsburgh, PA, USA. Linkovf@duq.edu.ORCID http://orcid.org/0000-0002-3707-0104
Yue-Fang Chang *Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0003-0080-4597
Harshitha RamananDepartment of Health, Exercise & Applied Science, John G. Rangos Sr. School of Health Sciences, Duquesne University, Pittsburgh, PA, USA.ORCID http://orcid.org/0009-0009-4525-8359
Richard S MorganDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0009-0003-1800-8545
Kathleen M McTigueDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-0752-1576
Anne E F DimmockPenn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.ORCID http://orcid.org/0000-0002-9422-7745
Rebecca Bascom *Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.ORCID http://orcid.org/0000-0001-5875-3476
Daniel J Kass *Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-6597-7830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/rationaleIdiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive disease of unknown origin. Establishing the epidemiology of IPF has been challenging due to diagnostic complexity, poor survival, low prevalence, and heterogeneity of ascertainment methodologies.

objectivesThis research aimed to estimate the rates of IPF in central and western Pennsylvania and to pilot the use of capture recapture (CR) methods to estimate the disease incidence.

methodsWe identified adults ≥ 30 years old diagnosed with IPF (by ICD-9/10 coding) between 2013 to 2021 from two health systems (UPMC Health System and Penn State Health) participating in the PaTH Clinical Research Network. We extracted information on patients' sex, race, date of birth and 3-digit zip code from electronic health records (EHR). Incidence rate of IPF among Pennsylvania residents was calculated using three case definitions (broad and two restricted) and piloted the use of CR in estimating IPF incidence.

resultsIPF incidence rates were 8.42, 6.95 and 4.4 per 100,000 person-years for the unrestricted (n = 3148), partially restricted (n = 2598) and fully restricted (n = 1661) samples, respectively. Low case overlap between two sites resulted in a highly inflated estimate of IPF incidence, using the CR methodology.

conclusionsThe rate of IPF in central and western Pennsylvania was similar to previously published statistics. The application of CR to IPF epidemiology could be further investigated in health systems with greater overlap of patients utilizing more than one system.

Indexed as

Idiopathic Pulmonary FibrosisAdultAgedAged, 80 and overFemaleHumansIncidenceMaleMiddle AgedPennsylvaniaPilot ProjectsEpidemiologyInterstitial lung disease

Identifiers

PMID40065350
PMCPMC11895235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.