Evidence map›Paper›PMID 40065344›Full record

ArticleBMC public health2025

Gender-specific association between serum uric acid levels and hypertension in East China: a cross-sectional study.

Dan Liu, Xiang Zheng, Jing Zhu, Jianshu Yang, Li Lu, Xiaodong Ji, Jie Hui, Yongqin Luo

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dan LiuHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Xiang ZhengHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Jing ZhuHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Jianshu YangHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Li LuHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Xiaodong JiHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China.
Jie HuiDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 21506, China. huijie_2020@163.com.
Yongqin LuoHealth Management Center, The First Affiliated Hospital of Soochow University, No. 188, Shizi Street, Gusu District, Suzhou, 215006, China. luoyongqinzone@163.com.

Funding

Suzhou Medical-Industrial Col laborative Innovation Research Project SLJ201907
6 · The paper itself

Abstract

backgroundThis cross-sectional study aimed to investigate the correlation between serum uric acid (SUA) levels and the incidence of sex-specific high blood pressure in East China.

methodsA total of 27,075 patients (14,399 males and 12,676 females) were enrolled in this study. The participants were grouped based on their SUA levels. Thereafter, the quartile (Q1-Q4) nodes of male SUA and female SUA were calculated based on the differences in the mean values of male and female SUA levels. The odds ratio (OR) and 95% confidence interval (CI) were calculated to evaluate the correlation between SUA and high blood pressure incidence.

resultsSUA expression levels were higher in males than in females. High SUA levels in males were positively correlated with hypertension. In females, high SUA levels were positively correlated with both hypertension and diabetes. After adjusting for confounding risk factors, SUA was confirmed as an independent risk factor for high blood pressure among males. Additionally, significant differences were observed between SUA and high blood pressure in body mass index (BMI) as well as diabetes subgroup analysis among males. There was a sex-specific correlation between SUA, high diastolic blood pressure (DBP), and high systolic blood pressure (SBP). Finally, there was a linear dose-response relationship between SUA and high blood pressure in males.

conclusionSUA is an independent risk factor for the incidence of high blood pressure after adjustment for other potential confounding risk factors in males. Sex-specific differences were also observed between SUA levels and high DBP or SBP.

Indexed as

HypertensionUric AcidAdultAgedChinaCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedRisk FactorsSex FactorsUric AcidCardiovascular diseaseDiastolic blood pressureSerum uric acidSystolic blood pressure

Identifiers

PMID40065344
PMCPMC11895223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.