ArticleThe journal of headache and pain2025
The burden of migraine and tension-type headache in Asia from 1990 to 2021.
Article in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Long-term safety and continued clinical benefit of erenumab 70 mg in Asian patients with chronic migraine: an open-label extension of the phase 3 DRAGON study.The journal of headache and pain · 2026Trial
- Driving Mechanisms and Future Trends of Migraine and Tension-Type Headache Burden in G20 Countries: A Comparative Analysis Utilizing Decomposition Analysis and Explainable Machine Learning.Pain and therapy · 2026Article
- Review
- Pressure Pain Thresholds Across Nerve-Related and Muscular Sites in Frequent Episodic Tension-Type Headache: An Exploratory Case-Control Study.Journal of clinical medicine · 2026Article
- Associations between oral migraine preventive regimens and CGRP monoclonal antibody initiation: real-world evidence from a resource-limited setting.BMC neurology · 2026Article
- Trends in the Disease Burden of Migraine Among Women of Reproductive Age (15-49 Years) in Low- and Middle-Income Countries, 1990-2023.International journal of women's health · 2026Article
- Association Between the Frailty Index and Self-Reported Headache in Middle-Aged and Older Chinese Adults: An Analysis of the China Health and Retirement Longitudinal Study.Pain research & management · 2026Article
- Altered network homogeneity of the default mode network in patients with tension-type headache.Frontiers in neurology · 2026Article
- A Comprehensive Mendelian Randomization Study of Bidirectional Causal Relationships Between Pain and Mental Disorders.Journal of pain research · 2026Article
- Mapping the brain cell-specific regulatory architecture of migraine: a single-cell causal framework nominating inhibitory-neuronal BTBD16 and astrocytic RIMS1 as therapeutic targets.The journal of headache and pain · 2025Article
- Causal proteomic insights into drug target discovery for tension-type headache.The journal of headache and pain · 2025Article
- Associations between temporomandibular disorders/bruxism and head and neck pains: a bidirectional Mendelian randomization study.Journal of oral & facial pain and headache · 2025Article
- Global, regional, and national epidemiology of neurological disorders and subcategories: incidence and disability-adjusted life years, 1990-2021.European journal of medical research · 2025Article
- Global trends and regional disparities in the burden of headache disorders, 1990-2021: a comprehensive analysis of the global burden of disease study.Frontiers in neurology · 2025Article
- Analysis of headache burden Chinese in the global context from 1990 to 2021.Frontiers in neurology · 2025Article
- Ultrasound-guided block of the superior cervical ganglion for migraine attacks: a propensity score-matched retrospective study.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Trends and comparative analysis of the burden of migraine in China and globally from 1990 to 2021: an analysis based on the 2021 global burden of disease study.Frontiers in neurology · 2025Article
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5 authors.
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Abstract
backgroundIn recent years, headache diseases have spread throughout the world, causing great suffering and even severe disability to patients, and increasing the burden on health care systems. However, studies of specific regions are rare. The purpose of our study is to comprehensively analyze the current situation and trends of headache diseases in Asia between 1990 and 2021, to provide details of headache diseases in Asia, and to provide scientific data to support health development strategies.
methodsData from the Global Burden of Disease (GBD) 2021 database were used to calculate the incidence, prevalence and disability-adjusted life years (DALYs) of headache disorders in Asia from 1990 to 2021. Differences between years, ages, sexes and countries were also assessed, and we evaluated the correlation between epidemiological and sociodemographic indices (SDIs).
resultIn 2021, there were approximately 683,514,637 cases of migraine in Asia. Meanwhile, there are now 1,130,221,326 cases associated with tension-type headache (TTH) in Asia. Specifically, the age-standardized DALYs (ASDR) [607 cases per 100,000 people (95% UI: 70 - 1,363)] for migraine were highest in Southeast Asia, and the ASDR [422 cases per 100,000 people (95% UI: 86-938)] was lowest in high-income countries of the Asia-Pacific region. ASDR [67 cases per 100,000 people (95% UI: 18-236)] was highest for TTH in Central Asia and lowest for ASDR [43 cases per 100,000 people (95% UI: 13-141)] in East Asia. In addition, women are the key population for migraine and TTH prevalence. In Asia, there were negative and positive correlations between migraine and TTH and SDI, respectively.
conclusionsHeadache disorders pose a serious threat to the quality of life and safety of patients in Asia, increasing the burden on society, and this impact will continue to grow. Our findings suggest that active public awareness, improved guidelines, and better disease management are necessary to expand the public and healthcare system's attention to headache disorders, and thereby gain a greater advantage in combating the burden of headache disorders in the future.
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