Evidence map›Paper›PMID 40065200›Full record

ArticleBMC gastroenterology2025

Descriptive analysis of common causes of upper gastrointestinal bleeding in pediatric patients in Kerman: a study from 2022 to 2023.

Maryam Gholami Shahrebabak, Nazanin Zeinali Nezhad, Mohammad Aref Azadmanesh, Amirhossein Shahpar, Azam Gholami Shahrebabak

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Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Maryam Gholami ShahrebabakDepartment of Pediatrics, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Nazanin Zeinali NezhadPhysiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran. nazaninzeinali4@gmail.com.
Mohammad Aref AzadmaneshKerman University of Medical Sciences, Kerman, Iran.
Amirhossein ShahparGastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman, Iran.
Azam Gholami ShahrebabakDepartment of Pediatrics Afzalipour Hospital, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper gastrointestinal bleeding (UGIB) in pediatric patients is a significant clinical concern requiring prompt diagnosis and management. This study aims to provide a descriptive analysis of the common causes of UGIB in pediatric patients in Kerman, Iran.

methodsA cross-sectional study was conducted at Afzalipour Hospital, Kerman, from January 2022 to December 2023. All pediatric patients under 18 years with UGIB were included. Data on demographics, clinical presentation, and endoscopic findings were collected and analyzed.

resultsA total of 120 patients were included, with a mean age of 8.8 ± 4.7 years. Hematemesis was the predominant presenting feature (57.5%). All patients underwent endoscopy, with a diagnostic yield of 88.4%. Gastric erosion was the most common cause of UGIB (33.3%), followed by esophageal varices (13.3%). The etiology varied across age groups, with Mallory-Weiss syndrome being the second most common cause in infants. Blood transfusion was required in 31.67% of patients.

conclusionThis study highlights the common causes and clinical features of pediatric UGIB in Kerman, Iran. Gastric erosion (33.3%) was the most frequent cause, and endoscopy achieved a high diagnostic yield (88.4%). Blood transfusion was necessary in 31.67% of patients. These findings emphasize the need for age-specific diagnostic strategies and reflect regional differences in UGIB etiology.

Indexed as

Esophageal and Gastric VaricesGastrointestinal HemorrhageAdolescentBlood TransfusionChildChild, PreschoolCross-Sectional StudiesEndoscopy, GastrointestinalFemaleHematemesisHumansInfantIranMaleMallory-Weiss SyndromeStomach UlcerBleedingEndoscopyGastrointestinalPediatric

Identifiers

PMID40065200
PMCPMC11895127

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.