ReviewNature reviews. Neurology2025
Mechanistic insights into the interaction between epilepsy and sleep.
Review in Nature reviews. Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Epilepsy as a predictor of subjective memory and executive dysfunction in American children and adults, with sleep as a relevant factor.Epilepsy & behavior : E&B · 2026Article
- Sleep Smarter: Optimal Sleep May Preserve Cognition and Reduce Dementia Risk in Focal Epilepsy.Epilepsy currents · 2026Article
- Inroads into epilepsy through high-frequency oscillations: Achievements and benchmark areas for improvement.Epilepsia · 2026Review
- Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology.Epilepsia · 2026Review
- Article
- EEG Signal Classification with Data Augmentation for Epileptic Focus Localization and Deep Sleep Detection.Sensors (Basel, Switzerland) · 2026Article
- Circadian rhythms in pediatric neurocritical care: interfaces and opportunities.Frontiers in neurology · 2026Review
- Brain-wide properties of slow waves across vigilance states.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Comparative Assessment of Quality of Life and Serum S100B in Epilepsy Treated with Newer and Conventional Drugs: A Pharmacoeconomic Perspective.Journal of epilepsy research · 2025Article
- A clinical grade neurostimulation implant for hierarchical control of physiological activity.bioRxiv : the preprint server for biology · 2025Article
- Article
- Dynamic Interplay Between Wake Slow Waves and Epileptiform Discharges in the Epileptogenic Zone.Neurology · 2025Article
- Thalamic engagement by epileptic spikes as a mechanism for widespread slow oscillation-spindle decoupling.Epilepsia · 2025Article
- Article
- EEG focal delta slowing in focal epilepsy - A didactic review.Clinical neurophysiology practice · 2025Review
- Global, regional, and national epilepsy of unknown cause incidence and mortality, 1990-2036: cross-national health inequalities and predictive analytics.Frontiers in neurology · 2025Article
- "Adverse event reports of seizure for insomnia medication from 1967 to 2023". The challenge of using hypnotic medication in people with epilepsy.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological evidence has demonstrated associations between sleep and epilepsy, but we lack a mechanistic understanding of these associations. If sleep affects the pathophysiology of epilepsy and the risk of seizures, as suggested by correlative evidence, then understanding these effects could provide crucial insight into the basic mechanisms that underlie the development of epilepsy and the generation of seizures. In this Review, we provide in-depth discussion of the associations between epilepsy and sleep at the cellular, network and system levels and consider the mechanistic underpinnings of these associations. We also discuss the clinical relevance of these associations, highlighting how they could contribute to improvements in the management of epilepsy. A better understanding of the mechanisms that govern the interactions between epilepsy and sleep could guide further research and the development of novel approaches to the management of epilepsy.
Indexed as
Identifiers
40065066What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.