ArticleScientific reports2025
Prevalence of extrapulmonary tuberculosis and factors influencing successful treatment outcomes among notified cases in South India.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Efficacy and safety of VPM1002 and Immuvac in preventing tuberculosis: phase 3 randomised clinical trial (PreVenTB trial).BMJ (Clinical research ed.) · 2026Trial
- Design, synthesis, and biological evaluation of coumarin derivatives against tuberculosis: a pharmacophore-based approach.Molecular diversity · 2026Article
- Peritoneal Tuberculosis Presenting as Massive Ascites in Pregnancy: A Case Report.Clinical case reports · 2026Article
- Coexisting Pyogenic and Tuberculous Liver Abscess in Uncontrolled Diabetes: A Diagnostic Challenge.Clinical case reports · 2026Article
- Article
- A three-phase epidemiological fluctuation framework of extrapulmonary tuberculosis in Fuyang, China: a retrospective study.Frontiers in public health · 2026Article
- Article
- Treatment outcomes and clinical characteristics in diabetic versus non-diabetic sinonasal tuberculosis.Bioinformation · 2026Article
- Hidden in Plain Sight: Peritoneal Tuberculosis Mimicking Ovarian Neoplasm-A Case Report.Tropical medicine and infectious disease · 2025Article
- Article
- Evaluating the Gaps in the Diagnosis and Treatment in Extra-Pulmonary Tuberculosis Patients Under National Tuberculosis Elimination Programme (NTEP) Guidelines: A Multicentric Cohort Study.Tropical medicine and infectious disease · 2025Article
- Evaluation of host-immune biomarker signatures as multiplex qPCR diagnostic assays: a pilot study toward meeting WHO target product profiles for TB diagnosis in India.Frontiers in tuberculosis · 2025Article
- Unveiling the Conundrum: Genital Tuberculosis with Omental Tubercles and Uterine Leiomyoma Masquerading as Malignancy.International journal of applied & basic medical researchArticle
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13 authors.
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Abstract
Tuberculosis (TB) remains a significant public health issue globally, with extra pulmonary tuberculosis (epTB) accounting for a considerable number of TB cases. This study aims to improve our understanding of epTB epidemiology by evaluating treatment outcomes and identifying factors associated with positive and negative treatment results in epTB patients. A retrospective study was conducted from January 1, 2016, to December 31, 2019. EpTB and rifampicin-resistant epTB were identified using the GeneXpert MTB/RIF assay. Logistic regression analysis was performed to determine the associated risk factors. Among the 4,526 patients with extra pulmonary tuberculosis, the positivity rate of Mycobacteriuum tuberculosis among the epTB was 16.5%, and the rate of rifampicin-resistant epTB was 4.83%. Most of patients had lymphadenitis TB (n = 348, 38.79%), followed by those with pus (n = 241, 31.95%). Of 746 epTB cases, 679 patients (91.02%) achieved successful treatment outcomes. Of the 36 patients with rifampicin-resistant epTB, 30 (83.3%) exhibited successful treatment outcomes. Tuberculous peritonitis (OR: 1.58), aspirate (OR: 1.59), gastric lavage (OR: 1.45), biopsy (OR: 1.73), Tuberculosis meningitis (TBM) (OR: 1.46), and tissue samples (OR: 3.33) were all significantly associated with unfavourable treatment outcomes. Patients with extrapulmonary tuberculosis (epTB) aged between 35 and 44 had a significantly higher likelihood of experiencing unsuccessful outcomes (OR = 1.79; 95% CI: 0.74-4.31, p = 0.0912). Additionally, individuals with a history of alcohol use showed a higher likelihood of poor outcomes (OR = 1.90; 95% CI: 0.25-14.42). Moreover, tuberculosis patients who used tobacco also had an increased likelihood of unfavourable treatment outcomes (OR = 2.62; 95% CI: 0.35-19.68).The study indicated that the rate of favourable treatment outcomes among epTB patients surpassed the World Health Organization's target of ≥ 90%. However, a significant number of patients were lost to follow-up during treatment.
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