Evidence map›Paper›PMID 40065046›Full record

ArticleScientific reports2025

Combination of gut microbiota, proinflammatory cytokine, and

Jeongshin An, Bom Sahn Kim, Hai-Jeon Yoon

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jeongshin AnInstitute of Convergence Medicine Research, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, 1071 Anyangcheon‑ro, Yangcheon‑gu, Seoul, 07985, Republic of Korea.
Bom Sahn KimDepartment of Nuclear Medicine, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, 260 Gonghang-daero, Gangseo-gu, Seoul, 07804, Republic of Korea. kbomsahn@ewha.ac.kr.
Hai-Jeon YoonDepartment of Nuclear Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, 1071 Anyangcheon‑ro, Yangcheon‑gu, Seoul, 07985, Republic of Korea. haijeon.yoon@ewha.ac.kr.

Funding

Korean Association for Women Surgeons 202201770001National Research Foundation of Korea RS-2024-00449684National Research Foundation of Korea RS-2024-00453521
6 · The paper itself

Abstract

Breast cancer occurs at a younger age compared to western countries in South Korea. Despite advancements in treatment methods such as targeted therapy and immunotherapy, the increasing number of patients underscores the importance of improving disease-free survival (DFS). In this study, we evaluated the associations between gut microbiota composition, inflammatory cytokine levels, and breast cancer recurrence in preoperative patients. Additionally, we developed a composite prognostic index by integrating these factors with PET/CT indices and clinical prognostic factors. This study showed that Prevotella abundance was significantly higher in the DFS group than in the recurrence group, and higher Prevotella abundance was associated with lower levels of the inflammatory cytokine IL-1β. Survival analysis revealed that patients with low Prevotella abundance and high IL-1β levels had a higher risk of breast cancer recurrence. PET markers, such as SUV

Indexed as

Breast NeoplasmsCytokinesFluorodeoxyglucose F18Gastrointestinal MicrobiomeNeoplasm Recurrence, LocalAdultAgedDisease-Free SurvivalFemaleHumansMiddle AgedPositron-Emission TomographyPositron Emission Tomography Computed TomographyPrevotellaPrognosisCytokinesFluorodeoxyglucose F1818F-FDG PETBreast cancerGut microbiotaPro-inflammatory cytokineRecurrenceSpleen uptakeTumor uptake

Identifiers

PMID40065046
PMCPMC11894217

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.