Evidence map›Paper›PMID 40065021›Full record

Trial reportScientific reports2025

The effect of MIND diet on sleep status, mental health, and serum level of BDNF in overweight/obese diabetic women with insomnia: a randomized controlled trial.

Mona Golmohammadi, Vahideh Ebrahimzadeh Attari, Yahya Salimi, Lotfollah Saed, Seyed Mostafa Nachvak, Mehnoosh Samadi

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mona GolmohammadiStudent Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Vahideh Ebrahimzadeh AttariDepartment of Biochemistry and Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Yahya SalimiSocial Development & Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Lotfollah SaedFaculty of Medical Science, Kurdistan University of Medical Sciences, Kurdistan, Iran.
Seyed Mostafa NachvakDepartment of Nutritional Sciences, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran. smnachvak@hotmail.com.
Mehnoosh SamadiDepartment of Nutritional Sciences, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran. mehnoosh_samadi@yahoo.com.

Funding

Kermanshah University of Medical Sciences 4020342
6 · The paper itself

Abstract

Insomnia is common in type 2 diabetes mellitus (T2DM) and affects mental health and quality of life. The present study aimed to examine the efficacy of MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on the anthropometric measurements, sleep quality, depression, anxiety, and serum levels of cortisol and brain derived neurotrophic factor (BDNF) in type 2 diabetic women with insomnia. This randomized controlled trial (RCT) involved 44 type 2 diabetic women with insomnia, aged 30 to 65 years, who were randomly assigned to be under the MIND low-calorie diet (n = 22) or a low-calorie diet (LCD) as the control group (n = 22) for 12 weeks. The above-mentioned variables were assessed at the beginning and the end of intervention. Following the MIND diet for 12 weeks accompanied by the significant decrease of waist circumference and significant improvement of sleep quality, depression, and anxiety compared to the control group. In addition, the MIND diet vs. LCD group exhibited a significant reduction in the cortisol levels and a significant increase in BDNF. This study provides promising evidence of the effectiveness of the MIND diet in improving the sleep quality, mental health, and some related biochemical parameters in diabetic women with insomnia.Trial registration: IRCT20181111041611N8.

Indexed as

Brain-Derived Neurotrophic FactorDiabetes Mellitus, Type 2Diet, MediterraneanObesityOverweightSleepSleep Initiation and Maintenance DisordersAdultAgedAnxietyDepressionFemaleHumansHydrocortisoneMental HealthMiddle AgedBDNF protein, humanBrain-Derived Neurotrophic FactorHydrocortisoneBDNFDiabetes mellitusMental healthMIND dietSleep quality

Identifiers

PMID40065021
PMCPMC11893750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.