ArticleNature communications2025
Observation of topological hydrogen-bonding domains in physical hydrogel for excellent self-healing and elasticity.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- HomologousMaterials today. Bio · 2026Article
- Physically Crosslinked Conductive Organic Gel with Excellent Elasticity and Environmental Stability.Gels (Basel, Switzerland) · 2026Article
- Highly Stable Quasi-Solid Thermocells for Continuous Power Generation Across a Broad Humidity Range.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Bioinspired Sarcomeric Double-Network Hydrogels for Programmable Mechanics with Ultralow Hysteresis.Gels (Basel, Switzerland) · 2026Article
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- Supramolecular Multiple Stimuli-Responsive Conductive Hydrogel for Flexible Sensing.Gels (Basel, Switzerland) · 2026Article
- Efficient Recovery of Collagen from Tannery Waste Materials and Its Integration into Functional Hydrogel Systems.Gels (Basel, Switzerland) · 2026Article
- Unveiling the rheological secrets of hydrogels: from lab to clinical translation.RSC advances · 2026Review
- Hydrogels-Advanced Polymer Platforms for Drug Delivery.Polymers · 2026Review
- A review of self-healing mechanisms for the application of conductive electronic products.RSC advances · 2026Review
- Biomimetic Gradient Lubrication Hydrogel Contrived by Self-Reinforced MOFs Nanoparticle Network.Nano-micro letters · 2026Article
- Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Development and characterization of egg white protein-pullulan-pomegranate peel polyphenol composite films for berry fruits preservation.Food chemistry: X · 2025Article
- Development and Characterization of a Novel Erucyl Ultra-Long-Chain Gemini Surfactant.Polymers · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Physical hydrogels, three-dimensional polymer networks with reversible cross-linking, have been widely used in many developments throughout the history of mankind. However, physical hydrogels face significant challenges in applications due to wound rupture and low elasticity. Some self-heal wounds with strong ionic bond throughout the network but struggle to immediately recover during cyclic operation. In light of this, a strategy that achieves both self-healing and elasticity has been developed through the construction of topological hydrogen-bonding domains. These domains are formed by entangled button-knot nanoscale colloids of polyacrylic-acid (PAA) with an ultra-high molecular weight up to 240,000, further guiding the polymerization of polyacrylamide to reinforce the hydrogel network. The key for such colloids is the self-assembly of PAA fibers, approximately 4 nm in diameter, and the interconnecting PAA colloids possess high strength, simultaneously acting as elastic scaffold and reversibly cross-linking near wounds. The hydrogel completely recovers mechanical properties within 5 h at room temperature and consistently maintains >85% toughness in cyclic loading. After swelling, the hydrogel has 96.1 wt% of water content and zero residual strain during cycling. Such physical hydrogel not only provides a model system for the microstructural engineering of hydrogels but also broadens the scope of potential applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.