ReviewBioresources and bioprocessing2025
Advances in biosynthesis of chiral amide herbicides and the key enzymes: dimethenamid-P and S-metolachlor as case studies.
Review in Bioresources and bioprocessing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Arenediazonium-generated aryl radical and nitrile coupling cascade under neat and catalyst-free conditions: green synthesis of anilides.RSC advances · 2026Article
- Picolinamides with β-Thiophosphorylated Amine Residues as a Useful Scaffold to Generate Biologically Active Pd(II) Pincer Complexes.International journal of molecular sciences · 2026Article
- Core-shell molecularly imprinted polymer for selective recognition and detection of S-metolachlor in aqueous samples.Scientific reports · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Chiral amide herbicides represent a significant class of agrochemicals, widely used for effective weed control. Prominent examples include S-metolachlor and dimethenamid-P, both of which share the intermediate (S)-1-methoxy-2-propylamine, a key structural component in their synthesis. Developing green and sustainable methods for producing this intermediate is crucial for enhancing the environmental and economic feasibility of herbicide manufacturing. Biosynthesis, with its advantages in sustainability and efficiency, has emerged as a pivotal approach in pesticide production. This review explores the classification and current development status of chiral amide herbicides, including their varieties and applications in the agricultural market. It outlines the synthesis pathways for S-metolachlor and dimethenamid-P, covering both chemical and biosynthetic routes. The review also highlights the functional properties of the key enzymes involved in the biosynthesis of (S)-1-methoxy-2-propylamine, focusing on the potential for enzyme engineering and creation to optimize these pathways. The challenges and future development directions for amide herbicides are discussed, with an emphasis on overcoming synthetic and ecological barriers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.