Evidence map›Paper›PMID 40064724›Full record

ReviewCurrent allergy and asthma reports2025

Herbal Medicine in Acute and Chronic Sinusitis; Still a Cinderella?

Alexios Vardouniotis, Maria Doulaptsi, Georgia Liva, Ioannis Vlastos, Alexander Karatzanis, Emmanuel Prokopakis

Abstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexios VardouniotisENT Consultant, NHS Treatment Center, Portsmouth, UK.
Maria DoulaptsiDepartment of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece.
Georgia LivaDepartment of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece.
Ioannis VlastosDepartment of Otorhinolaryngology, Aghia Sophia Children's Hospital, Athens, Greece.
Alexander KaratzanisDepartment of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece.
Emmanuel ProkopakisDepartment of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece. eprokopakis@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo set the context of current knowledge regarding the role of herbal medicine in acute and chronic rhinosinusitis treatment. RECENT

findingsIt is estimated that adults experience 1-3 episodes of viral rhinosinusitis per year and this number increases up to 8-10 episodes in preschool children. The symptoms of acute rhinosinusitis tend to significantly overlap with symptoms of other upper respiratory infections, making the diagnosis quite difficult. The division of rhinosinusitis into bacterial or non-bacterial is clinically important in order to determine appropriate treatment and the administration of antibiotic treatment. Treatment of acute rhinosinusitis is symptomatic and includes nasal rinsing, decongestants, corticosteroids, and combinations of the above. Herbal medicine has been traditionally underestimated in Western world. Nowadays, however, treatment of diseases with the use of medicinal plant treatments is gaining more and more followers. In this context, certain herbal extracts have been tested for viral, post- viral and chronic rhinosinusitis. Phytoneering is an innovative pharmaceutical technique in research and production of herbal medicines. Herbal extracts produced with phytoneering vary in quality and active substances. In terms of quality, safety and efficacy, herbal medicines are at least on par with synthetically produced medicines, having significantly less unwanted side effects. Certain herbal extracts have been tested, and in cases of acute rhinosinusitis are effective. In chronic sinusitis those extracts show promising results and might prove a good alternative without side effects.

Indexed as

Herbal MedicinePhytotherapyPlant ExtractsRhinitisSinusitisAcute DiseaseChronic DiseaseHumansPlants, MedicinalPlant ExtractsAcute rhinosinusitisChronic rhinosinusitisHerbal extractHerbal medicinePhytoneering

Identifiers

PMID40064724
PMCPMC11893696

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.