Evidence map›Paper›PMID 40064716›Full record

ArticleInnere Medizin (Heidelberg, Germany)2025

[A rare differential diagnosis of fever of unknown origin].

Sabrina Welland, Linus Risser, René Abu Isneineh

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In one paragraph

Article in Innere Medizin (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabrina WellandKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Linus RisserKlinik für Rheumatologie und Immunologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
René Abu IsneinehKlinik für Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. abuisneineh.rene@mh-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 22-year-old male patient with a clinical picture similar to that of sepsis was diagnosed with macrophage activation syndrome in adult Still's disease on the basis of clinical and laboratory criteria. The diagnostic work-up included the differentiated clarification of a persistent fever syndrome and the differential diagnosis of hemophagocytic lymphohistiocytosis. Immunosuppressive therapy with dexamethasone, immunoglobulins and anakinra was initiated and a sustained clinical remission was achieved.

Indexed as

Fever of Unknown OriginLymphohistiocytosis, HemophagocyticMacrophage Activation SyndromeStill's Disease, Adult-OnsetAntirheumatic AgentsDexamethasoneDiagnosis, DifferentialHumansImmunosuppressive AgentsInterleukin 1 Receptor Antagonist ProteinMaleYoung AdultAntirheumatic AgentsDexamethasoneImmunosuppressive AgentsInterleukin 1 Receptor Antagonist ProteinAdult-onset Still’s diseaseFever of unknown originHemophagocytic lymphohistiocytosisMacrophage activation syndromeYamaguchi criteria

Identifiers

PMID40064716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.