Evidence map›Paper›PMID 40064711›Full record

ArticleClinical reviews in allergy & immunology2025

The Role of Coagulation/Fibrinolysis Biomarkers in Pathophysiology, Disease Severity, and Treatment Response in Patients with Urticaria: A Scoping Review.

Hai-Yan Qin, Xian-Jun Xiao, Pei-Wen Xue, Di Qin, Si-Qi Wang, Ying Li, Yun-Zhou Shi, Li-Tao Pan

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical reviews in allergy & immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hai-Yan Qin *Department of Acupuncture and Massage, Shenzhen Second People's Hospital, Futian District, Sungang West Road, Shenzhen, Guangdong Province, 3002, China.
Xian-Jun Xiao *Chengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China.
Pei-Wen Xue *Chengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China.
Di QinChengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China.
Si-Qi WangChengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China.
Ying LiChengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China.
Yun-Zhou ShiChengdu University of Traditional Chinese Medicine, No. 37 Shi Er Qiao Street, Chengdu, 610075, China. shiyunzhou@cdutcm.edu.cn.
Li-Tao PanDepartment of Acupuncture and Massage, Shenzhen Second People's Hospital, Futian District, Sungang West Road, Shenzhen, Guangdong Province, 3002, China. ltpan@email.szu.edu.cn.

Funding

National Natural Science Foundation of China 82105026National Natural Science Foundation of China 82205283National Natural Science Foundation of Sichuan 2023NSFSC0693National Natural Science Foundation of Sichuan 24NSFSC1549San-ming Project of Medicine in Shenzhen No.szzysm202311020Shenzhen Special Project for Basic Research (Natural Science Foundation) - General Project of Basic Research JCYJ20240813141021028
6 · The paper itself

Abstract

The pathology of urticaria is complex. Recently, researchers have widely focused on the role that the coagulation/fibrinolysis system plays in the pathology of urticaria. The potential of coagulation/fibrinolysis biomarkers as disease severity or treatment response biomarkers remains uncertain, lacking comprehensive analysis in previous studies. Hence, we performed a scoping review to thoroughly analyze coagulation/fibrinolysis biomarkers that may predict disease progression and treatment response of urticaria. Data from 71 studies showed that chronic spontaneous urticaria (CSU) was the most-studied subtype (39 articles), with D-dimers being the most researched marker (56 articles). Twenty-one biomarkers were investigated, and ten biomarkers were significantly correlated with disease severity. Specifically, D-dimers (26 articles) and prothrombin fragment 1 + 2 (F

Indexed as

BiomarkersBlood CoagulationFibrinolysisUrticariaFibrin Fibrinogen Degradation ProductsHumansPrognosisSeverity of Illness IndexTreatment OutcomeBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment DCoagulation/fibrinolysis biomarkersD-dimerProthrombin fragment 1 + 2Scoping reviewUrticaria

Identifiers

PMID40064711
PMCPMC11893642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.