Evidence map›Paper›PMID 40064284›Full record

ReviewInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2025

Tuberculosis and HIV coinfection: Progress and challenges towards reducing incidence and mortality.

Bianca Sossen, Mmamapudi Kubjane, Graeme Meintjes

Abstract readReview
In one paragraph

Review in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Construction of RecombinantPathogens (Basel, Switzerland) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Preparing for Tuberculosis Vaccine M72/AS01Infectious diseases and therapy · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bianca SossenDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town, South Africa. Electronic address: bianca.sossen@uct.ac.za.
Mmamapudi KubjaneHealth Economics and Epidemiology Research Office, Wits Health Consortium, Parktown Johannesburg, South Africa.
Graeme MeintjesDepartment of Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town, South Africa; Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

Funding

HIV-associated Tuberculosis Training Program (HATTP)D43TW010559 · FIC · UNIVERSITY OF CAPE TOWN · PI Graeme Ayton Meintjes · 2017 to 2026
$3.0M
FIC NIH HHS D43 TW010559
6 · The paper itself

Abstract

HIV-associated tuberculosis (HIV-TB) is associated with disproportionate mortality: approximately 24% of the 660,000 individuals with TB and HIV died, compared to 11% of those without HIV dying from TB in 2023. HIV is a key driver of ongoing high TB incidence in many countries, particularly in the World Health Organization Africa region, and TB is the leading cause of hospitalization in people with HIV (PWH) globally. Significant developments have occurred recently concerning the prevention, screening, diagnosis, and management of HIV-TB. Antiretroviral therapy and novel regimens for TB preventive therapy are now known to decrease TB incidence and improve survival. The use of Xpert Ultra (Cepheid, USA) and urine Determine

Indexed as

AIDS-Related Opportunistic InfectionsAnti-Retroviral AgentsAntitubercular AgentsHIV InfectionsTuberculosisDrug Resistance, BacterialGlobal HealthHospitalizationHumansIncidenceMycobacterium tuberculosisSouth AfricaSputumWorld Health OrganizationAnti-Retroviral AgentsAntitubercular AgentsControlEliminationGlobalHIVTuberculosis

Identifiers

PMID40064284
PMCPMC12957463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.