Evidence map›Paper›PMID 40064137›Full record

ArticleInfant behavior & development2025

Associations between maternal adverse childhood experiences and mind-mindedness: An analysis of mother-infant interaction.

Ana Paula Constantino Fernandes, Celia Maria de Araujo, Anoek Marjelle Oerlemans, Marcos Roberto Fanton, Cintia Sanches, Ivaldo da Silva, Ana Carolina Coelho Milani, Jonathan Posner, Andrea Parolin Jackowski, Claudia Berlim de Mello

Abstract read
In one paragraph

Article in Infant behavior & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Paula Constantino FernandesDepartment of Psychobiology, Universidade Federal de São Paulo, Brazil.
Celia Maria de AraujoDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Anoek Marjelle OerlemansDepartment of Pedagogical and Educational Sciences, University of Groningen, Groningen, the Netherlands.
Marcos Roberto FantonDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Cintia SanchesDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Ivaldo da SilvaDepartment of Gynecology, Universidade Federal de São Paulo, Brazil.
Ana Carolina Coelho MilaniDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Jonathan PosnerDepartment of Psychiatry & Behavioral Sciences, Duke University, Durham, United States.
Andrea Parolin JackowskiDepartment of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.
Claudia Berlim de MelloDepartment of Psychobiology, Universidade Federal de São Paulo, Brazil. Electronic address: claudia.berlim@unifesp.br.

Funding

Maternal adversity, inflammation, and neurodevelopment: How intergenerational processes perpetuate disadvantage in a low-resource settingR01MH121070 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Cristiane S. Duarte, Andrea Parolin Jackowski · 2020 to 2026
$2.8M
NIMH NIH HHS R01 MH121070
6 · The paper itself

Abstract

Adverse childhood experiences (ACEs) can influence parenting behaviours and have lasting effects on child development. This study investigated how maternal ACEs affect mind-mindedness during interactions between 69 Brazilian mothers and their six-month-old infants, and the role of stress in this relationship. Maternal vocalisations were coded for appropriate and non-attuned mind-related comments according to the Mind-Mindedness Coding Manual. The number of maternal ACEs was assessed using the CDC-Kaiser ACE Study Questionnaire. Current stress, postnatal depression, depression, anxiety, adverse life events, and resilience were assessed using the Perceived Stress Scale, Edinburgh Postnatal Depression Scale, Depression Scale Patient Health Questionnaire, Generalized Anxiety Disorder, the Inventory of Major Life Events, and the Resilience Scale, respectively. General Linear Models analysed associations between variables. The results showed no direct link between ACEs and mind-mindedness. However, stress moderated the relationship between maternal ACEs and appropriate mind-related comments. These findings suggest that maternal exposure to ACEs affects how mothers interpret their infants' mental states, particularly under stress. Understanding these relationships can guide interventions to support maternal mental health and foster positive parent-infant interactions, potentially preventing the intergenerational transmission of trauma.

Indexed as

Adverse Childhood ExperiencesMother-Child RelationsMothersParentingStress, PsychologicalAdultAnxietyBrazilFemaleHumansInfantMaleYoung AdultAdverse childhood experiencesMentalizationMind-mindednessMother-child relations

Identifiers

PMID40064137
PMCPMC12148694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.