ArticlePloS one2025
The prevalence and correlation of cancer-related fatigue and locomotive syndrome in geriatric cancer patients.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association between fat-free mass index and severe locomotive syndrome in patients with cancer: sex-specific cutoff values.International journal of clinical oncology · 2026Article
- Bodyweight increase since early adulthood as a risk factor for mobility decline: a 7-year longitudinal study of 10,316 Japanese adults aged ≥ 40 years.Archives of public health = Archives belges de sante publique · 2026Article
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5 authors.
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Abstract
objectiveTo explore the relationship between cancer-related fatigue (CRF) and locomotive syndrome (LS) among Chinese older adults with cancer.
methodsThis study was a cross-sectional survey. Staged random sampling method was employed to enroll 500 geriatric cancer patients from the Oncology Center of Jiangnan University Hospital in Wuxi, Jiangsu Province, China. Data were collected using General Information Questionnaire, Cancer Fatigue Scale and the Geriatric Locomotive Function Scale. χ2 test, Logistic regression analysis and Spearman analysis were utilized to analyze the data.
resultsA total of 466 geriatric cancer patients were enrolled in this survey. The occurrence of CRF was 43.8%, and the occurrence of LS was 30.9%. LS were risk factors for the occurrence of CRF in geriatric cancer patients. Advanced old age, fear of falling, comorbid with chronic diseases and CRF were risk factors for LS. CRF was positively associated with LS (r = 0.446, P < 0.001).
conclusionOur findings indicate a potential link between CRF and LS. By addressing LS from various aspects, including controlling the number of complications due to advanced old age and other factors, as well as spreading proper fall-related knowledge and controlling the awareness of fear of falling, healthcare professionals can indirectly alleviate CRF symptoms and improve the overall quality of life for these patients.
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