SynthesisPloS one2025
Effectiveness of rehabilitation training on radiotherapy-related abnormalities of voice function in head and neck cancer patients: A systematic review and meta-analysis.
Synthesis in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- [Non-surgical rehabilitation of patients with head and neck cancer].Magyar onkologia · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundAbnormal speech function caused by radiotherapy will affect the normal communication of patients with head and neck cancer (HNC) and even interrupt their social life. Rehabilitation Training is widely used to improve articulatory abnormalities in patients with HNC. However, the effectiveness of these rehabilitation measures in restoring the voice function of HNC patients is still unknown.
objectiveThis study aimed to systematically examine the effects of rehabilitation training on radiotherapy-related voice function and quality of life in patients with HNC.
methodsThe databases PubMed, Web of Science, EMBASE, Cochrane Library, CINAHL, CNKI, Wan Fang, and SinoMed were searched for studies published from inception through October 2024. Randomized controlled trials of rehabilitation training to improve voice function abnormalities associated with radiotherapy for HNC were included, and two investigators independently performed the literature review. Meta-analysis was performed using RevMan 5.4 software to determine statistical heterogeneity based on P-values and I2 values.
results13 randomized controlled trials involving 710 participants were included. Meta-analysis showed that rehabilitation training significantly affected the patients' maximum phonation time(MD=1.53, 95%CI=[0.83, 2.23], P<0.0001, Grade Moderate), smoothed cepstral peak prominence(MD=-0.59, 95%CI=[-0.89, -0.29], P=0.0001, Grade Moderate), social communication abilities(MD=-2.60, 95%CI=[-5.14, -0.07], P=0.04, Grade Moderate), and quality of life(MD=8.49, 95%CI=[3.06, 13.92], P=0.002, Grade Moderate).
conclusionsRehabilitation training is an effective approach for ameliorating abnormal voice functions after radiotherapy for HNC. However, there is no consensus on the optimal frequency, periodicity, and follow-up of interventions for rehabilitation training. More studies are still required to determine the optimal intervention effect for ameliorating speech function abnormalities in patients with HNC after radiotherapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.