Evidence map›Paper›PMID 40063324›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Rapid diagnosis of urinary tract infection with miniaturised point-of-care cultivation on a dipstick.

Emre Iseri, Gino Jakobsson, Sofia Bertling, Volkan Özenci, Oskar Ekelund, Wouter van der Wijngaart, Alex van Belkum

Abstract readReview
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In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Point of care antimicrobial susceptibility testing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emre IseriUtilizerTM AB, Kaptensvägen 5C, 132 46 Saltsjö Boo, Stockholm, Sweden.
Gino JakobssonUtilizerTM AB, Kaptensvägen 5C, 132 46 Saltsjö Boo, Stockholm, Sweden.
Sofia BertlingUtilizerTM AB, Kaptensvägen 5C, 132 46 Saltsjö Boo, Stockholm, Sweden.
Volkan ÖzenciDepartment of Clinical Microbiology, Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska University Hospital, KarolinskaInstitutet, Stockholm, Sweden.
Oskar EkelundClinical Microbiology, Region Kronoberg. National Reference Laboratory for AST. WHO Collaborating Centre, Vaxjo, Sweden.
Wouter van der WijngaartDivision of Micro and Nanosystems, KTH Royal Institute for Technology, Malvinas Väg 10, Stockholm, Sweden.
Alex van BelkumIndependant Microbiology Advisor, Jan Van Goyenplein 31, 2231 MM, Rijnsburg, The Netherlands. alexvanbelkum@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUrinary Tract InfectionAQ1 (UTI) affects over 400 million people annually and globally and is a major reason for empiric antibiotic prescription by general practitioners (GPs).

backgroundA problem related to microbiological UTI diagnosis is the current lack of point of care (POC) diagnostics. In addition, remote settings, including low and middle income countries (LMIC), are hard to service. Compliance with requirements posed by the In Vitro Diagnostic Regulation (IVDR) and adherence to guidelines as defined by professional user groups are mandatory to pursue. In addition, the World Health Organisation (WHO) promotes optimization of antimicrobial use and more adequate microbiological diagnostics to cure UTI and combat antimicrobial resistance (AMR).

methodsMiniaturised chromogenic bacterial cultivation including rapid antimicrobial susceptibility testing (RAST) at the POC can be successfully used for the diagnosis of UTI. Using small and cost-effective dipsticks containing chromogenic cultivation media, UTI-causing bacteria can be detected, quantified and identified with good sensitivity and specificity.

conclusionAccess to such trustworthy, easy-to-use and cost-efficient diagnostic tools at the POC would offer more timely results for optimised antibiotic treatment. This will improve UTI therapy and prevent AMR.

Indexed as

BacteriaBacteriological TechniquesPoint-of-Care SystemsPoint-of-Care TestingUrinary Tract InfectionsAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsSensitivity and SpecificityAnti-Bacterial AgentsChromogenic cultivationMiniature dipstick assayPoint of care diagnosticsUrinary tract infection

Identifiers

PMID40063324

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.