Evidence map›Paper›PMID 40063090›Full record

ReviewRadiologie (Heidelberg, Germany)2025

[Technical foundations of large language models].

Christian Blüthgen

Abstract readEnglish AbstractReview
In one paragraph

Review in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christian BlüthgenInstitut für Diagnostische und Interventionelle Radiologie, Universitätsspital Zürich, Universität Zürich, Rämistrasse 100, 8091, Zürich, Schweiz. christian.bluethgen@usz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLarge language models (LLMs) such as ChatGPT have rapidly revolutionized the way computers can analyze human language and the way we can interact with computers.

objectiveTo give an overview of the emergence and basic principles of computational language models.

methodsNarrative literature-based analysis of the history of the emergence of language models, the technical foundations, the training process and the limitations of LLMs.

resultsNowadays, LLMs are mostly based on transformer models that can capture context through their attention mechanism. Through a multistage training process with comprehensive pretraining, supervised fine-tuning and alignment with human preferences, LLMs have developed a general understanding of language. This enables them to flexibly analyze texts and produce outputs of high linguistic quality.

conclusionTheir technical foundations and training process make large language models versatile general-purpose tools for text processing, with numerous applications in radiology. The main limitation is the tendency to postulate incorrect but plausible-sounding information with high confidence.

Indexed as

LinguisticsNatural Language ProcessingHumansLarge Language ModelsChatGPTComputational linguisticsGenerative artificial intelligenceLarge language modelsNatural language processing

Identifiers

PMID40063090
PMCPMC11937190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.