ArticleACS nano2025
Breathing Laser-Spectral Mapping of Cavity-Enhanced Redox Reactions with Subcellular Resolution.
Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Precise and dynamic observation of redox reactions in living organisms holds significant importance for the study of physiological processes and pathological mechanisms. However, the current technologies still make it challenging to monitor this process in a nondestructive and highly sensitive manner. Herein, we introduced a bioactive laser approach for ultrasensitive and real-time monitoring of intracellular redox reactions. Resazurin, as a popular cell viability assay reagent, has lasing behaviors and photostability, which makes it suitable for the development of bioactive lasers. Due to the strong interactions of light and matter within the laser cavity, subtle changes in resazurin concentration during the redox reaction can be translated into detectable wavelength shifts in the lasing spectrum. With narrow laser peaks, the sensing resolution can reach down to 30 pM per 10 pm wavelength shift. Combined with a scanning platform, we mapped the intracellular and intercellular heterogeneities in metabolism. Further applications in cell identification, oxidative stress assessment, and drug evaluation revealed the universal applicability of this method in cell assays and biomedical analysis, providing insights into disease diagnosis and drug screening.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.