ArticleScandinavian journal of work, environment & health2025
Combined exposure to night work and noise in relation to hyperglycemia among long-term night workers: a nationwide population-based prospective cohort study.
Article in Scandinavian journal of work, environment & health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study investigated the association between combined exposures and hyperglycemia incidence, as well as the dose-response relationship between the duration of night work and hyperglycemia among long-term night workers.
methodsIn this prospective cohort study, 12 716 night workers from the nationwide population were recruited. Hyperglycemia incidence was based on the one-year change in fasting blood glucose levels. Occupational noise exposure was defined as exposure to 8-hour time-weighted average sound levels of ≥85 decibels. Personal factors, including body mass index, and work-related factors, like monthly night work duration, were assessed. Multivariable logistic and linear regression models were used to explore the association.
resultsIn the multivariate logistic analyses, each additional day of night work was associated with an increased risk of hyperglycemia [adjusted odds ratio 1.05, 95% confidence interval (CI) 1.02-1.07]. In the normal fasting glucose group, each additional day of night work was associated with a linear increase of +0.07% (95% CI +0.03% - +0.12%) in the change in fasting glucose levels, and noise exposure was associated with a linear increase of +1.34% (95% CI +0.55% - +2.12%) increase in fasting glucose levels. Furthermore, the population exposed to noise and working ≥10 days of night work had a significantly higher increase of fasting glucose levels (β +5.71%, 95% CI +4.48% - +6.95%), with significant interaction effects (P for interaction <0.01).
conclusionsThe possible dose-response relationship between duration of night work and changes in fasting glucose levels was found. The combined exposure to night work and noise posed a higher risk for hyperglycemia than exposure to night work alone.
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