Evidence map›Paper›PMID 40062700›Full record

ArticleBiotechnology and bioengineering2025

High-Efficiency PET Degradation With a Duo-Enzyme System Immobilized on Magnetic Nanoparticles.

Siddhi Kotnis, Siddhant Gulati, Qing Sun

Abstract read
In one paragraph

Article in Biotechnology and bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Yeast-Mediated Plastic Biodegradation.International journal of molecular sciences · 2026
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Siddhi KotnisDepartment of Chemical Engineering, Texas A&M University, College Station, Texas, USA.ORCID 0009-0006-7144-2748
Siddhant GulatiDepartment of Chemical Engineering, Texas A&M University, College Station, Texas, USA.
Qing SunDepartment of Chemical Engineering, Texas A&M University, College Station, Texas, USA.

Funding

A deep learning and experiment integrated platform for stable mRNA vaccines developmentR01AI165433 · NIAID · TEXAS ENGINEERING EXPERIMENT STATION · PI qing sun · 2022 to 2026
$1.8M
NIAID NIH HHS R01 AI165433This work was supported by funds provided by a National Science Foundation (NSF) grant to Q. S. (2203715), USA; NSF Emerging Frontiers in Research and Innovation (EFRI) to Q. S. (2132156), USA; Texas A&M Excellence Fund X-grants to Q. S., Texas A&M, USA; Texas A&M Targeted Proposal Teams (TPT) grant to Q. S., Texas A&M, USA; NIH NIAID R01 to Q. S. (R01AI165433), Texas A&M, USA. This work was partially supported by the National Science Foundation (NSF) under Award No. 2330245, which funds the Engineering Research Center for Carbon Utilization Redesign through Biomanufacturing-Empowered Decarbonization (CURB).
6 · The paper itself

Abstract

The widespread consumption of PET worldwide has necessitated the search for environment-friendly methods for PET degradation and recycling. Among these methods, biodegradation stands out as a promising approach for recycling PET. The discovery of duo enzyme system PETase and MHETase in 2016, along with their engineered variants, has demonstrated significant potential in breaking down PET. Previous studies have also demonstrated that the activity of the enzyme PETase increases when it is immobilized on nanoparticles. To achieve highly efficient and complete PET depolymerization, we immobilized both FAST-PETase and MHETase at a specific ratio on magnetic nanoparticles. This immobilization resulted in a 2.5-fold increase in product release compared with free enzymes. Additionally, we achieved reusability and enhanced stability of the enzyme bioconjugates.

Indexed as

Enzymes, ImmobilizedMagnetite NanoparticlesPolyethylene TerephthalatesEnzymes, ImmobilizedMagnetite NanoparticlesPolyethylene Terephthalatesbioconjugate formationco‐immobilizationnanoparticle enzyme assemblyPET degradation

Identifiers

PMID40062700
PMCPMC12067030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.