Evidence map›Paper›PMID 40062687›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025

Home-based heat therapy lowers blood pressure and improves endothelial function in older adults.

Ysabella I Ruiz-Pick, Heidi L Cope, Rauchelle E Richey, Amy M Moore, Tyson C Garfield, Albert H Olivencia-Yurvati, Steven A Romero

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ysabella I Ruiz-PickHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.ORCID 0000-0002-4701-9943
Heidi L CopeHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.ORCID 0009-0008-9764-8052
Rauchelle E RicheyHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.ORCID 0000-0002-7090-1782
Amy M MooreHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.
Tyson C GarfieldDepartment of Internal Medicine and Geriatrics, The University of North Texas Health Science Center, Fort Worth, Texas, United States.
Albert H Olivencia-YurvatiHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.
Steven A RomeroHuman Vascular Physiology Laboratory, Department of Physiology and Anatomy, The University of North Texas Health Science Center, Fort Worth, Texas, United States.ORCID 0000-0002-2014-7806

Funding

Training in the Neurobiology of Aging and Alzheimer's DiseaseT32AG020494 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI ROBERT Clinton BARBER, NATHALIE SUMIEN · 2002 to 2026
$6.9M
American Heart Association (AHA) 23DIVSUP1069441American Heart Association (AHA) TPA958179HHS | NIH | National Institute on Aging (NIA) T32AG020494NIA NIH HHS T32 AG020494
6 · The paper itself

Abstract

Advancing age is associated with vascular dysfunction and hypertension, both of which increase cardiovascular event risk. Heat therapy has emerged as a novel intervention to improve cardiovascular health in various populations. Therefore, we tested the hypothesis that home-based lower body heat therapy would reduce blood pressure and improve endothelium-dependent vasodilation in older adults. Ambulatory blood pressure monitoring was performed in 19 older adults (67 ± 7 yr) before and after 8 wk of a sham intervention or heat therapy. Endothelium-dependent vasodilation of the superficial femoral artery was assessed via flow-mediated dilation. Participants were provided with a pair of tube-lined pants connected to a portable water circulator to perform the home-based sessions. Water temperature was set to 31°C for sham and 51°C for heat therapy, resulting in target skin temperatures of ∼33°C and ∼40°C, respectively. Participants were instructed to wear the pants 4 days/wk for 60 min each session. Adherence was 100% for both groups. Heat therapy reduced ambulatory daytime systolic blood pressure by Δ -5 ± 8 mmHg, but was unchanged for the sham group (Δ 1 ± 6 mmHg;

Indexed as

Blood PressureEndothelium, VascularHypertensionHyperthermia, InducedAgedBlood Pressure Monitoring, AmbulatoryFemaleFemoral ArteryHot TemperatureHumansMaleMiddle AgedVasodilationagingblood pressureheat therapyvascular function

Identifiers

PMID40062687
PMCPMC12053574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.