ArticleTurkish journal of obstetrics and gynecology2025
Predictive value of homocysteine levels in embryo culture media for embryo selection in infertile patients with endometriosis.
Article in Turkish journal of obstetrics and gynecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the possible ability of homocysteine (Hcy) levels in embryo culture media for estimating better invitro fertilization outcomes in endometriosis patients. Materials and Methods: Nineteen women with endometriosis who were admitted to Cerrahpaşa Medical Faculty, Department of Obstetrics and Gynecology, Infertility Outpatient Clinic with the diagnosis of infertility were included in the study. The results of intracytoplasmic sperm injection treatments were recorded and Hcy levels in the embryo culture were evaluated. The results were compared with those of the control patients without endometriosis, who had previously been admitted to our clinic for assisted reproductive technology. Results: Mean Hcy levels in the culture media of the endometriosis group and non-endometriosis group were 4.31±0.48 µmol/L and 4.15±1.44 µmol/L, respectively (p>0.05). Pregnancy was achieved in 3 patients in the endometriosis group, while 13 pregnancies were obtained in the non-endometriosis group (p>0.05). When all cases were evaluated, the mean value of Hcy in the culture medium was found to be 3.60±0.84 µmol/L in the patients with a pregnancy and 4.21±0.84 µmol/L in the group that failed to achieve a pregnancy, and this difference was statistically significant (p<0.05). Conclusion: Difference between mean Hcy levels in the culture media of the endometriosis group and non-endometriosis group was statistically non-significant. Further studies with larger groups are needed for evaluating the association of Hcy with infertility in endometriosis patients. Mean Hcy levels in the group of patients who succeeded in conceiving were statistically higher than the group of patients who failed to conceive. It may be suggested that Hcy levels in the embryo culture media can predict the achievement of a pregnancy independently from some conditions which may adversely affect the embryo quality, such as endometriosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.