Evidence map›Paper›PMID 40062472›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2025

The spatiotemporal development of mesenteric lymphatic changes in the

Keith Keane, Matthew Stephens, Simon Roizes, Jingna Xue, Shan Liao, Pierre-Yves von der Weid

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Lymphatic alterations in Crohn's disease: the villain or victim.American journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Keith KeaneDepartment of Physiology and Pharmacology, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Matthew StephensDepartment of Physiology and Pharmacology, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0571-4531
Simon RoizesDepartment of Physiology and Pharmacology, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jingna XueDepartment of Microbiology, Immunology and Infectious Diseases, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-5981-1938
Shan LiaoDepartment of Microbiology, Immunology and Infectious Diseases, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Pierre-Yves von der WeidDepartment of Physiology and Pharmacology, Inflammation Research Network, The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-6020-393X

Funding

Crohn's and Colitis Canada (Crohn et Colite Canada) 623941Lymphedema Research and Education Program, Snyder Institute for Chronic Diseases, University of Calgary
6 · The paper itself

Abstract

Crohn's disease (CD) is a chronic inflammatory bowel disease, which also encompasses significant alterations of the mesenteric lymphatic system. Whether these changes are a mere consequence of or directly contribute to the inflammation is unknown. Here, we characterized the spatial and temporal development of these events in the

Indexed as

Crohn DiseaseIleitisLymphangiogenesisLymphatic VesselsMesenteryTumor Necrosis Factor-alphaAnimalsDisease Models, AnimalIleumMaleMiceMice, Inbred C57BLPeroxidasePeroxidaseTumor Necrosis Factor-alphaCrohn’s diseaseimmunofluorescence imaginginflammationlymphatic vesselmesentery

Identifiers

PMID40062472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.