Evidence map›Paper›PMID 40062413›Full record

ReviewCytoskeleton (Hoboken, N.J.)2025

Phosphorylation at the Helm: Kinase-Mediated Regulation of Primary Cilia Assembly and Disassembly.

Andrea Lacigová, Lukáš Čajánek

Abstract readReview
In one paragraph

Review in Cytoskeleton (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrea LacigováLaboratory of Cilia and Centrosome Biology, Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.ORCID https://orcid.org/0009-0004-7001-4376
Lukáš ČajánekLaboratory of Cilia and Centrosome Biology, Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.ORCID https://orcid.org/0000-0003-2914-8589

Funding

Czech Science Foundation (22-13277S)
6 · The paper itself

Abstract

The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying this control still awaits full resolution. Through their enzymatic activity, kinases function as flexible yet highly controllable regulators of a vast variety of cellular processes. Their activity ranges from cell cycle control to regulation of cell motility, signal transduction, and metabolism. This review focuses on the emerging role of kinases in primary cilia biology. We underscore their functions in primary cilia formation, maintenance, and resorption while examining available models and the respective mechanisms of their actions.

Indexed as

CiliaAnimalsHumansPhosphorylationSignal Transductionkinasephosphorylationprimary ciliumsubstrate

Identifiers

PMID40062413
PMCPMC12620543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.