Evidence map›Paper›PMID 40062311›Full record

ArticleClinical case reports2025

An Unusual Presentation of Peri-Lead Edema Following Deep Brain Stimulation for Parkinson's Disease: A Case Report and Review of the Literature.

V S Witzig, R Pjontek, A Höllig, J Schiefer, M Wiesmann, H Clusmann, J B Schulz, F Holtbernd

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

V S WitzigDepartment of Neurology RWTH Aachen University Aachen Germany.ORCID https://orcid.org/0000-0002-1141-6736
R PjontekDepartment of Neurosurgery RWTH Aachen University Aachen Germany.
A HölligDepartment of Neurosurgery RWTH Aachen University Aachen Germany.
J SchieferDepartment of Neurology RWTH Aachen University Aachen Germany.
M WiesmannDepartment of Neuroradiology University Hospital RWTH Aachen Aachen Germany.
H ClusmannDepartment of Neurosurgery RWTH Aachen University Aachen Germany.
J B SchulzDepartment of Neurology RWTH Aachen University Aachen Germany.
F HoltberndDepartment of Neurology RWTH Aachen University Aachen Germany.ORCID https://orcid.org/0000-0002-2348-7064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peri-lead edema (PLE) after deep brain stimulation may mimic brain infection on magnetic resonance imaging (MRI). We present a case of symptomatic PLE with annular contrast enhancement on MRI suggestive of an infectious cause. We show that careful clinical evaluation and laboratory testing, in addition to neuroimaging, are essential to guide treatment and to avoid unnecessary interventions in PLE cases with a favorable spontaneous course.

Indexed as

deep brain stimulationmovement disordersneuromodulationParkinson's diseaseperi‐lead edema

Identifiers

PMID40062311
PMCPMC11885058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.