Evidence map›Paper›PMID 40062172›Full record

ArticleCureus2025

Isolated Testicular Metastasis From Prostate Cancer: A Rare Presentation 15 Years Posttreatment.

Tauqir Aslam Waraich, Syed Yousaf Khalid, Asadullah Aslam, Claudio Lizarralde, Syed Jaffry

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tauqir Aslam WaraichDepartment of Urology, Letterkenny University Hospital, Letterkenny, IRL.
Syed Yousaf KhalidDepartment of Cardiothoracic Surgery, St. James's Hospital, Dublin, IRL.
Asadullah AslamDepartment of Urology, Kingsbridge Healthcare Group, Belfast, IRL.
Claudio LizarraldeDepartment of Histopathology, Galway Clinic, Galway, IRL.
Syed JaffryDepartment of Urology, University Hospital Galway, Galway, IRL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testicular metastases from prostate cancer (PCa) are exceedingly rare and are typically accompanied by other metastatic sites. We present the case of an 82-year-old male patient who developed isolated testicular metastasis 15 years after undergoing radiotherapy and androgen deprivation therapy (ADT) for localized PCa. The patient presented with a palpable left testicular mass, which was confirmed to be a metastatic prostate adenocarcinoma by histopathological and immunohistochemical analyses. Orchiectomy was performed for both diagnostic and therapeutic purposes, resulting in a significant decline in serum PSA levels. The patient continued ADT with regular monitoring, and no further metastases were detected. This case highlights the importance of long-term surveillance and advanced diagnostic techniques for detecting the rare metastatic presentations of PCa. Although isolated testicular metastases may have a better prognosis than other metastatic patterns, optimal postorchiectomy management remains uncertain, underscoring the need for further research and a multidisciplinary approach.

Indexed as

androgen deprivation therapyprostate-specific antigenprostatic adenocarcinomatestestesticular metastasis

Identifiers

PMID40062172
PMCPMC11888571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.