ReviewCureus2025
Spinal Cord Stimulation for Functional Restoration in Spinal Cord Injury: A Narrative Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Transspinal direct current stimulation alters neuronal excitability but not homosynaptic inhibition in human spinal cord injury: a pilot clinical trial.Experimental brain research · 2025Trial
- A comprehensive review on pain: Model, target, therapy, and prospect (Review).International journal of molecular medicine · 2026Review
- Mechanisms and Applications of Conductive Biomaterials in Spinal Cord Injury Repair.Biomaterials research · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal cord injury (SCI) represents a significant medical challenge, leading to profound and often debilitating neurological deficits that adversely affect motor, sensory, and autonomic functions. Traditional rehabilitation strategies, while essential in the management of SCI, often exhibit limited efficacy in restoring lost functions, leaving many individuals with permanent disabilities. In this context, spinal cord stimulation (SCS) emerges as a novel and promising therapeutic approach with the potential to enhance neurological recovery by promoting neural plasticity and activating residual neural pathways. This narrative review provides a comprehensive examination of SCS, elucidating its underlying mechanisms of action, technological advancements, clinical applications, and associated outcomes in patients with SCI. Both invasive (epidural) and noninvasive (transcutaneous) SCS are discussed, emphasizing their therapeutic potentials with current established evidence. This narrative review integrates findings from preclinical and clinical studies, highlighting the role of SCS in facilitating functional recovery. Furthermore, this review highlights the challenges faced in the field, including variability in patient responses, lack of standardized stimulation protocols, and the need for further research to substantiate long-term outcomes. We conclude by discussing future directions for SCS research, including the development of closed-loop systems and innovative brain-spine interfaces, which may optimize treatment delivery and enhance functional recovery in individuals with SCI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.