Evidence map›Paper›PMID 40061968›Full record

ArticleWorld journal of gastrointestinal surgery2025

Prognostic value of combined detection of alpha-fetoprotein, plasma prothrombin activity, and serum prealbumin in acute-on-chronic liver failure.

Rui-Xian Duan, Ling Liu, Yan Wang, Wen-Ming Wu

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Article in World journal of gastrointestinal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rui-Xian DuanDepartment of Infectious Diseases, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan 030032, Shanxi Province, China.
Ling LiuDepartment of Pulmonary Diseases, Shanxi Provincial Integrated TCM and WM Hospital, Taiyuan 030013, Shanxi Province, China.
Yan WangDepartment of Infectious Diseases, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan 030032, Shanxi Province, China.
Wen-Ming WuClinical Laboratory, Shanxi Provincial People's Hospital, Taiyuan 030023, Shanxi Province, China. wu.wenming1007@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute-on-chronic liver failure (ACLF) is a liver disease based on chronic liver disease, which is significantly influenced by clinical treatment regimen and disease status, and despite the existence of multiple prognostic assessment indicators for ACLF, the overall sensitivity and accuracy are relatively low.

aimTo investigate the prognostic value of the combined detection of alpha-fetoprotein (AFP), plasma prothrombin activity (PTA), and serum prealbumin (PA) in ACLF.

methodsThis retrospective study included 87 patients with ACLF admitted from February 2021 to February 2023 and categorized them into the survival (

resultsAFP, PTA, and PA levels were markedly decreased in the death group than in the survival group (

conclusionThe combined detection of AFP, PTA, and PA levels demonstrates favorable diagnostic value for the short-term prognosis of patients with ACLF, featuring high sensitivity and specificity.

Indexed as

Acute-on-chronic liver failureAlpha-fetoproteinPrealbuminPrognostic valueProthrombin activity

Identifiers

PMID40061968
PMCPMC11885989

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