ArticleJournal of pharmacy & bioallied sciences2024
Cytotoxicity of Dhanwantharaarishtam on hiPSC Cells - An
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dhanwantharaarishtam is a traditional Ayurvedic herbal tonic used to improve digestion, promote lactation, and balance the Vata dosha. Aim: The study investigates the effects of Dhanwantharaarishtam, a traditional Ayurvedic tonic, on cell viability and cytotoxicity in human induced pluripotent stem cell (hiPSC) cultures. Methods: The impact of Dhanwantharaarishtam on hiPSC cells was analyzed over a 24 hour period. Results: Our results reveal significantly less cytotoxicity, with 80.1 ± 6.7% cell viability observed at 500 µg concentrations. Conversely, cell viability was reduced to 50.3 ± 4.15% at 1000 µg concentration. Conclusion: These findings suggest that while Dhanwantharaarishtam exhibits potent biological effects, including potential therapeutic benefits, its unsubstantial cytotoxic profile in hiPSC cells necessitates further investigation to elucidate its safety and potential applications in clinical settings. This study underscores the importance of rigorous evaluation of traditional herbal remedies for their efficacy and safety in modern biomedical research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.