Evidence map›Paper›PMID 40061709›Full record

ArticleJournal of pharmacy & bioallied sciences2024

Comparative Assessment of Blood Parameters Including RBC, Hb, PCV, Red Cell Indices, Serum Ferritin, and Salivary Candidal Growth in Female Patients with Iron Deficiency Anemia and Iron Deficiency.

Asra Saba, Garlapati Komali, Deepti Shrivastava, Mohammed A Alghafli, Faisal Maqbul Alazmi, Salman A S Aljudaya, Artak Heboyan, Kumar Chandan Srivastava

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asra SabaIndependent Researcher, Private Dental Practitioner, Hyderabad, Telangana, India.
Garlapati KomaliDepartment of Oral Medicine and Radiology, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Deepti ShrivastavaDepartment of Preventive Dentistry, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Mohammed A AlghafliDental Student, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Faisal Maqbul AlazmiDental Student, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Salman A S AljudayaDental Student, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.
Artak HeboyanDepartment of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia.
Kumar Chandan SrivastavaDepartment of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jouf University, Sakaka, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Iron deficiency anemia (IDA) is a microcytic-hypochromic anemia prevalent in African and South Asian countries including India. Along with systemic, it presents various oral manifestations that can be diagnosed in dental setups. Literature suggests that there is a state of iron deficiency before it manifests as anemia, which eventually creates an immunodeficient body state that predisposes to various opportunistic infections such as oral candidiasis. Objectives: The present study was designed to evaluate and compare various components of the blood picture including the hemoglobin (Hb%), red blood cell (RBC) count, RBC indices, hematocrit, peripheral blood smear and serum ferritin between iron deficiency (ID), IDA, and healthy subjects. The study also attempts to compare and assess the salivary samples of ID for Candida growth. Material and Methods: A total of 252 female patients of age groups ranging from 18 to 70 years were selected. The study consisted of three study groups, namely, Group A, IDA patients (clinical manifestations with pallor); Group B, ID patients (clinical manifestations without pallor); and Group C, age-matched healthy controls, with 84 in each group. The blood samples were collected to evaluate the hematological parameters including Hb%, RBC count, RBC indices, hematocrit, peripheral blood smear, and serum ferritin. Later, a saliva sample was collected from all study groups to assess the Candida growth. The obtained data were subjected to statistical analysis using SPSS version 20.0 software. Results: The results demonstrated that ID patients had normal blood parameters as healthy controls except for serum ferritin, while IDA patients had significantly ( Conclusion: Within the limitations of the current study, the results showed significantly reduced serum ferritin levels in ID, while other parameters were within the normal limits, and found tendency to develop Candida growth compared with the control subjects. Further studies are warranted to establish the association and causal relationship.

Indexed as

Candida growthiron deficiencyiron deficiency anemiawomen

Identifiers

PMID40061709
PMCPMC11888740

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