Evidence map›Paper›PMID 40061697›Full record

ArticleJournal of pharmacy & bioallied sciences2024

Protective Effect of Triphala Mediated by H

Shyam Sundar Shanker, Tiasha Dasgupta, Sharmila Hussain, H Annapoorni, Ramasamy Tamizhselvi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shyam Sundar ShankerDepartment of Prosthodontics Crown and Bridge, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (Deemed to be University), Tamil Nadu, India.
Tiasha DasguptaDepartment of Biosciences, School of Bioscience and Technology, Vellore Institute of Technology, Tamil Nadu, India.
Sharmila HussainDepartment of Prosthodontics Crown And Bridge, Madha Dental College and Hospital, Tamil Nadu, India.
H AnnapoorniDepartment of Prosthodontics Crown and Bridge, Meenakshi Ammal Dental College and Hospital, Meenakshi Academy of Higher Education and Research (Deemed to be University), Tamil Nadu, India.
Ramasamy TamizhselviDepartment of Biosciences, School of Bioscience and Technology, Vellore Institute of Technology, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: MacrophagesHydrogen sulfide (H2 S), an endogenously produced gasotransmitter, is a wellknown inflammatory agent production successfully controlled with triphala in macrophages. Materials and method: The ELISA analysis revealed that triphala extracts suppress the protein expression of NFκB (p65) and downregulation of the CSE gene expression. Moreover, in the presence of propargylglycine (PAG) the expression of NFκB and CSE gene was further reduced. Results: These results suggest that triphala could be a potent antiinflammatory effect that could be used for the treatment of many inflammatory disorders, including periimplantitis.

Indexed as

Hydrogen sulfideinflammationNF-κB (p65)Triphala

Identifiers

PMID40061697
PMCPMC11888769

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.