Evidence map›Paper›PMID 40061683›Full record

ArticleJournal of pharmacy & bioallied sciences2024

Effect of MMP Inhibitors on Shear Bond Strength of Adhesive to Dentin after Different Drying Techniques: An

Sheethal K Narayanan, Krishnan Hari, Joy Mathew, Anila Sukumaran, Basil Joy, Joel Mathew

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sheethal K NarayananDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Krishnan HariDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Joy MathewDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Anila SukumaranDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Basil JoyDepartment of Endodontics and Conservative Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.
Joel MathewDepartment of Pediatrics and Preventive Dentistry, Mar Baselios Dental College, Kothamangalam, Ernakulam, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Instead of excessive drying or wetness, maintaining an optimal moisture level on the dentin surface may enhance the polymerization process of certain monomers. The study was intended to contrast and evaluate the effect of Matrix metalloproteinases (MMPs) inhibitors (Chlorhexidine (CHX) and Doxycycline (DOX)) on the shear bond strength (SBS) of adhesive dentin interface after different drying techniques (blotting with tissue paper (TP) and damp cotton pellet (CP)). Materials and Methods: Ninety molars collected were split into three groups according to the materials used during the acid etching step: Group A (control): 37% phosphoric acid only; Group B: 37% phosphoric acid followed by 2% CHX; Group C: 37% phosphoric acid followed by 2% DOX. Each group was categorized into 2 subgroups based on the drying methods used after etching (TP and damp CP). A universal bonding agent was applied after this and composite restoration was placed onto the dentin and cured. The samples underwent thermocycling for 500 thermocycles for degradation of the adhesive surface. The SBS of the specimens was appraised with a universal testing machine until fracture. Results: The CHX group blotted with TP (20.98 ± 0.29 MPa) had the highest SBS among the study sample. This was eventually followed by the CHX group blotted with the CP (18.99 ± 0.28 MPa), DOX blotted with TP (19.73 ± 0.51 MPa), and DOX blotted with the CP (17.09 ± 0.55 MPa). The least SBS was observed in the control group blotted with TP (16.9 ± 0.22 MPa) and then by CP (13.78 ± 0.55 MPa). Conclusion: The study showed that CHX had a superior effect on the SBS when compared to DOX. Among the drying agents used TP yielded better results than drying with a damp CP. The overall SBS was high in the CHX group dried with TP and the least strength was shown by the control group where treatment with an MMP inhibitor was done.

Indexed as

Chlorhexidinedoxycyclinedrying techniquesMMP inhibitorsshear bond strength

Identifiers

PMID40061683
PMCPMC11888655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.