Evidence map›Paper›PMID 40061643›Full record

ArticleJournal of pharmacy & bioallied sciences2024

After Effects of Radiation on the Caries Status of Head and Neck Cancer Patients - A Six-Month Clinical Trial.

Upasana Reddy, Mithra N Hegde, Aditya Shetty, Mallikarjuna Rao Koduru, Neevan Dsouza

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Upasana ReddyDepartment of Conservative Dentistry and Endodontics, A.B.Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India.
Mithra N HegdeDepartment of Conservative Dentistry and Endodontics, A.B.Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India.
Aditya ShettyDepartment of Conservative Dentistry and Endodontics, A.B.Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India.
Mallikarjuna Rao KoduruDepartment of Radiotherapy and Oncology, K.S. Hegde Medical Institute of Health Sciences, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India.
Neevan DsouzaDepartment of Biostatistics, K.S. Hegde Medical Institute of Health Sciences, Nitte (Deemed to be University), Deralakatte, Mangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head and neck cancer patients undergoing radiation therapy (RT) are at an increased risk of dental caries due to radiation-induced damage to salivary glands. This study aimed to compare the effectiveness of three interventions-virgin coconut oil (VCO), casein phosphopeptide-amorphous calcium phosphate tooth mousse (TM), and amine fluoride mouthwash (MW)-in preventing caries among head and neck cancer patients' post-radiation therapy. Methods: A total of 102 head and neck cancer patients undergoing RT were enrolled. The participants were randomized to use one of three interventions: VCO, TM, or MW. Caries progression was assessed using the decayed-missing-filled-teeth (DMFT) index at baseline and after 6 months of RT. Differences in DMFT scores between the groups were analysed using statistical tests. Results: At the 6-month follow-up, significant differences in DMFT scores were observed between the VCO and MW groups ( Conclusions: Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) tooth mousse was found to be the most effective in preventing new caries and slowing the progression of existing carious lesions in head and neck cancer patients undergoing radiation therapy.

Indexed as

Anti-caries agentshead and neck cancerIMRTradiation cariesvirgin coconut oil

Identifiers

PMID40061643
PMCPMC11888752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.