Evidence map›Paper›PMID 40061534›Full record

ArticleJTCVS open2025

Temporal trends in the utilization, costs, and outcomes of concomitant left atrial appendage closure across a statewide collaborative.

Yas Sanaiha, Bob Kiaii, Jack C Sun, Michael Madani, Tom C Nguyen, Richard J Shemin, Peyman Benharash, University of California Cardiac Surgery Consortium

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yas SanaihaDivision of Cardiac Surgery, University of California Los Angeles, Los Angeles, Calif.
Bob KiaiiDivision of Cardiothoracic Surgery, Department of Surgery, University of California Davis Medical Center, Sacramento, Calif.
Jack C SunDivision of Cardiothoracic Surgery, University of California Irvine, Orange, Calif.
Michael MadaniSan Diego Health System, Division of Cardiovascular and Thoracic Surgery, University of California, La Jolla, Calif.
Tom C NguyenDepartment of Surgery, Division of Cardiothoracic Surgery, University of California San Francisco, San Francisco, Calif.
Richard J SheminDivision of Cardiac Surgery, University of California Los Angeles, Los Angeles, Calif.
Peyman BenharashDivision of Cardiac Surgery, University of California Los Angeles, Los Angeles, Calif.
University of California Cardiac Surgery Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: With the rising incidence of atrial fibrillation, left atrial appendage closure (LAAC) at the time of cardiac surgery remains an important adjunct. The present study characterized trends, associated resource utilization, and potential disparities in the use of left atrial appendage exclusion. Methods: Using a Society of Thoracic Surgeons regional academic collaborative database, we queried all adult patients undergoing coronary and valve procedures with concomitant LAAC between 2015 and 2021. Trends in LAAC, as well as the technique for closure, were evaluated. Multilevel hierarchical logistic modeling was applied to delineate factors associated with LAAC, accounting for patient and operative characteristics. Generalized linear models were developed to perform risk-adjusted incremental cost analysis. Results: Of the 8699 patients who met the study criteria, 1377 underwent left atrial appendage closure. Over the study period, the annual rate of LAAC increased from 16.7% to 30.8% ( Conclusions: Rates of LAAC are increasing but less common among female patients, as well as those requiring urgent/emergent interventions. LAAC did not significantly impact short-term mortality. Our results suggest that LAAC may be a high-value intervention among patient populations that have the greatest potential to derive its benefits.

Indexed as

coronary artery bypass graftingleft atrial appendage closurepostoperative atrial fibrillationsex-based disparitiesvalvular heart diseasevariation

Identifiers

PMID40061534
PMCPMC11883682

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.