Evidence map›Paper›PMID 40061508›Full record

ArticleIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

The Impact of Focal Lesions on Overall and Progression-free Survival in Multiple Myeloma.

Tugcan Alp Kirkizlar, Onur Kirkizlar, Selin Soyluoglu, Elif Gulsum Umit, Funda Ustun, Ahmet Muzaffer Demir

Abstract read
In one paragraph

Article in Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. The [European journal of nuclear medicine and molecular imaging · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tugcan Alp KirkizlarDepartment of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
Onur KirkizlarDepartment of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
Selin SoyluogluDepartment of Nuclear Medicine, Trakya University Medical Faculty, Edirne, Turkey.
Elif Gulsum UmitDepartment of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
Funda UstunDepartment of Nuclear Medicine, Trakya University Medical Faculty, Edirne, Turkey.
Ahmet Muzaffer DemirDepartment of Hematology, Trakya University Medical Faculty, Edirne, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: In this study, we aimed to reveal the incidence of ≥3 focal lesions (FLs) and analyze overall survival (OS) and progression-free survival (PFS) according to the number of FLs, as well as to identify mortality and PFS risk factors, in our newly diagnosed multiple myeloma (NDMM) patients. Materials and Methods: A total of 89 NDMM patients who underwent Results: While 57.3% of the patients had ≥3 FLs, 20.2% had no FL. The median OS and PFS were 55 and 43 months, respectively. The median survival time was 49 months for patients with ≥3 FLs and 101 months for patients with <3 FLs, with a statistically significant difference ( Conclusion: In our study, we observed significantly worse OS and PFS in patients with ≥3 FLs at diagnosis, and it is noteworthy that the OS was worse in those patients who did not undergo ASCT.

Indexed as

Focal lesionmortalitymultiple myelomapositron emission tomography/computerized tomography

Identifiers

PMID40061508
PMCPMC11884343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.